Clinical benefit of immune checkpoint inhibitors in elderly cancer patients: Current evidence from immunosenescence pathophysiology to clinical trial results.

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Title: Clinical benefit of immune checkpoint inhibitors in elderly cancer patients: Current evidence from immunosenescence pathophysiology to clinical trial results.
Authors: Ziogas DC; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: ziogasdc@gmail.com., Theocharopoulos C; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: hartheoch@gmail.com., Aravantinou K; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: k.aravantinou@hotmail.com., Boukouris AE; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: arisbouk@gmail.com., Stefanou D; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: dimitroulastef@hotmail.com., Anastasopoulou A; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: amanastasop@yahoo.gr., Lialios PP; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: lialios.panagiotispetros@gmail.com., Lyrarakis G; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: lyrarakis.g@hotmail.com., Gogas H; First Department of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece. Electronic address: helgogas@gmail.com.
Source: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Apr; Vol. 208, pp. 104635. Date of Electronic Publication: 2025 Jan 30.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0461
DOI:10.1016/j.critrevonc.2025.104635