Treatment failure patterns in early versus late introduction of CAR T-cell therapy in large B-cell lymphoma.

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Title: Treatment failure patterns in early versus late introduction of CAR T-cell therapy in large B-cell lymphoma.
Authors: Corona M; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ip A; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA., Brown S; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Luna A; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hematology Service, Hospital Ramon y Cajal, Madrid, Spain., Khatib H; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel., Flynn JR; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Devlin SM; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Landego I; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cassanello G; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy., Rejeski K; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Zuckerman T; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel., Dahi PB; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Scordo M; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lin RJ; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Kabat M; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA., Luttwak E; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pavkovic E; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel., Palomba ML; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park J; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Salles G; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schoder H; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Leithner D; Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Radiology, NYU Grossman School of Medicine, New York, NY, USA., Leslie LA; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA., Perales MA; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Beyar-Katz O; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel., Shah GL; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Shouval R; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. shouvalr@mskcc.org.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. shouvalr@mskcc.org.
Source: Bone marrow transplantation [Bone Marrow Transplant] 2025 Apr; Vol. 60 (4), pp. 491-498. Date of Electronic Publication: 2025 Feb 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8702459 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5365 (Electronic) Linking ISSN: 02683369 NLM ISO Abbreviation: Bone Marrow Transplant Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Corona+M%22">Corona M</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ip+A%22">Ip A</searchLink>; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Brown+S%22">Brown S</searchLink>; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Luna+A%22">Luna A</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Hematology Service, Hospital Ramon y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Khatib+H%22">Khatib H</searchLink>; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Flynn+JR%22">Flynn JR</searchLink>; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Devlin+SM%22">Devlin SM</searchLink>; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Landego+I%22">Landego I</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cassanello+G%22">Cassanello G</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rejeski+K%22">Rejeski K</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zuckerman+T%22">Zuckerman T</searchLink>; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Dahi+PB%22">Dahi PB</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Scordo+M%22">Scordo M</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lin+RJ%22">Lin RJ</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kabat+M%22">Kabat M</searchLink>; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Luttwak+E%22">Luttwak E</searchLink>; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pavkovic+E%22">Pavkovic E</searchLink>; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Palomba+ML%22">Palomba ML</searchLink>; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Salles+G%22">Salles G</searchLink>; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Schoder+H%22">Schoder H</searchLink>; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.; Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Leithner+D%22">Leithner D</searchLink>; Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Radiology, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Leslie+LA%22">Leslie LA</searchLink>; Lymphoma Service, Hackensack Meridian Health, New Jersey, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Perales+MA%22">Perales MA</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Beyar-Katz+O%22">Beyar-Katz O</searchLink>; Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.; The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Shah+GL%22">Shah GL</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shouval+R%22">Shouval R</searchLink>; Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. shouvalr@mskcc.org.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. shouvalr@mskcc.org.
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