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Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis.

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Title: Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis.
Authors: Inia JA; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, the Netherlands. Electronic address: jose.inia@tno.nl., van Nieuwkoop-van Straalen A; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands., Rolin B; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark., Staarup EM; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark., Mogensen CK; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark., Princen HMG; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands., van den Hoek AM; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.
Source: Journal of lipid research [J Lipid Res] 2025 Mar; Vol. 66 (3), pp. 100753. Date of Electronic Publication: 2025 Feb 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Inia+JA%22">Inia JA</searchLink>; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, the Netherlands. Electronic address: jose.inia@tno.nl.<br /><searchLink fieldCode="AU" term="%22van+Nieuwkoop-van+Straalen+A%22">van Nieuwkoop-van Straalen A</searchLink>; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jukema+JW%22">Jukema JW</searchLink>; Department of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rolin+B%22">Rolin B</searchLink>; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Staarup+EM%22">Staarup EM</searchLink>; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Mogensen+CK%22">Mogensen CK</searchLink>; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Princen+HMG%22">Princen HMG</searchLink>; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Hoek+AM%22">van den Hoek AM</searchLink>; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220376606%22">Journal of lipid research</searchLink> [J Lipid Res] 2025 Mar; Vol. 66 (3), pp. 100753. <i>Date of Electronic Publication: </i>2025 Feb 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0376606 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1539-7262 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222275%22">00222275 </searchLink><i>NLM ISO Abbreviation: </i>J Lipid Res <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jlr.2025.100753
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      – Code: eng
        Text: English
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              Text: 2025 Mar
              Type: published
              Y: 2025
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