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Cellular and biochemical heterogeneity contributes to the phenotypic diversity of transfusion-dependent β-thalassemia.

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Title: Cellular and biochemical heterogeneity contributes to the phenotypic diversity of transfusion-dependent β-thalassemia.
Authors: Theocharaki K; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Anastasiadi AT; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Delicou S; Thalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and their Complications, Hippokration General Hospital of Athens, Athens, Greece., Tzounakas VL; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Barla I; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Rouvela S; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Kazolia E; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Tzafa G; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Mpekoulis G; Department of Microbiology, Laboratory of Molecular Virology, Hellenic Pasteur Institute, Athens, Greece., Gousdovas T; Hematology Laboratory-Blood Bank, Aretaieio Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Pavlou E; Blood Bank and Haemophilia Unit, Hippokration General Hospital of Athens, Athens, Greece., Kostopoulos IV; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Velentzas AD; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Simantiris N; Department of Informatics, Ionian University, Corfu, Greece., Xydaki A; Thalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and their Complications, Hippokration General Hospital of Athens, Athens, Greece., Vassilaki N; Department of Microbiology, Laboratory of Molecular Virology, Hellenic Pasteur Institute, Athens, Greece., Voskaridou E; Centre of Excellence in Rare Haematological (Haemoglobinopathies) & Rare Metabolic (Gaucher Disease) Diseases, Laiko General Hospital, Athens, Greece., Aggeli IK; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Nomikou E; Blood Bank and Haemophilia Unit, Hippokration General Hospital of Athens, Athens, Greece., Tsitsilonis O; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Papageorgiou E; Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica, Egaleo, Greece., Thomaidis N; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Gikas E; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece., Politou M; Hematology Laboratory-Blood Bank, Aretaieio Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Komninaka V; Centre of Excellence in Rare Haematological (Haemoglobinopathies) & Rare Metabolic (Gaucher Disease) Diseases, Laiko General Hospital, Athens, Greece., Antonelou MH; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.
Source: Blood advances [Blood Adv] 2025 May 13; Vol. 9 (9), pp. 2091-2107.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Theocharaki+K%22">Theocharaki K</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Anastasiadi+AT%22">Anastasiadi AT</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Delicou+S%22">Delicou S</searchLink>; Thalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and their Complications, Hippokration General Hospital of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tzounakas+VL%22">Tzounakas VL</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Barla+I%22">Barla I</searchLink>; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Rouvela+S%22">Rouvela S</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kazolia+E%22">Kazolia E</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tzafa+G%22">Tzafa G</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Mpekoulis+G%22">Mpekoulis G</searchLink>; Department of Microbiology, Laboratory of Molecular Virology, Hellenic Pasteur Institute, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gousdovas+T%22">Gousdovas T</searchLink>; Hematology Laboratory-Blood Bank, Aretaieio Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Pavlou+E%22">Pavlou E</searchLink>; Blood Bank and Haemophilia Unit, Hippokration General Hospital of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kostopoulos+IV%22">Kostopoulos IV</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Velentzas+AD%22">Velentzas AD</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Simantiris+N%22">Simantiris N</searchLink>; Department of Informatics, Ionian University, Corfu, Greece.<br /><searchLink fieldCode="AU" term="%22Xydaki+A%22">Xydaki A</searchLink>; Thalassemia and Sickle Cell Unit, Expertise Center of Hemoglobinopathies and their Complications, Hippokration General Hospital of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Vassilaki+N%22">Vassilaki N</searchLink>; Department of Microbiology, Laboratory of Molecular Virology, Hellenic Pasteur Institute, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Voskaridou+E%22">Voskaridou E</searchLink>; Centre of Excellence in Rare Haematological (Haemoglobinopathies) & Rare Metabolic (Gaucher Disease) Diseases, Laiko General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Aggeli+IK%22">Aggeli IK</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Nomikou+E%22">Nomikou E</searchLink>; Blood Bank and Haemophilia Unit, Hippokration General Hospital of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Tsitsilonis+O%22">Tsitsilonis O</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Papageorgiou+E%22">Papageorgiou E</searchLink>; Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica, Egaleo, Greece.<br /><searchLink fieldCode="AU" term="%22Thomaidis+N%22">Thomaidis N</searchLink>; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gikas+E%22">Gikas E</searchLink>; Department of Chemistry, School of Science, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Politou+M%22">Politou M</searchLink>; Hematology Laboratory-Blood Bank, Aretaieio Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Komninaka+V%22">Komninaka V</searchLink>; Centre of Excellence in Rare Haematological (Haemoglobinopathies) & Rare Metabolic (Gaucher Disease) Diseases, Laiko General Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Antonelou+MH%22">Antonelou MH</searchLink>; Department of Biology, School of Science, National and Kapodistrian University of Athens, Athens, Greece.
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