High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.

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Title: High-throughput screening identifies Aurora kinase B as a critical therapeutic target for Merkel cell carcinoma.
Authors: Gelb T; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Garman KA; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Urban D; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Coxon A; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Gryder B; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Hill NT; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Miao L; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Lee T; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Lee O; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Chakka S; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Braisted J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Jarvis JE; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Glavin R; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Raj TS; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Xiao Y; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Difilippantonio S; Laboratory of Animal Sciences Program, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Wang AQ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Cheng KC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Lal-Nag M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850, USA., Brownell I; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. isaac.brownell@nih.gov.
Source: Nature communications [Nat Commun] 2025 Feb 12; Vol. 16 (1), pp. 1583. Date of Electronic Publication: 2025 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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