Adverse events and impact on quality of life of antibody-drug conjugates in the treatment of metastatic breast cancer: A systematic review and meta-analysis.

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Title: Adverse events and impact on quality of life of antibody-drug conjugates in the treatment of metastatic breast cancer: A systematic review and meta-analysis.
Authors: Perachino M; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.; Medical Oncology Service, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain., Blondeaux E; U. O. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Molinelli C; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Ruelle T; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Giannubilo I; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Arecco L; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Nardin S; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Razeti MG; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Borea R; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Favero D; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Lanzavecchia C; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Chiappe E; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy., Tomasello L; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Section of Medical Oncology, Department of Precision Medicine in Medical, Surgical and Clinical Care (Me.Pre.C.C), University of Palermo, Palermo, Italy., Mariamidze E; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Oncology and Hematology Department, Todua Clinic, Tbilisi, Georgia., Jankovic K; Clinic of Oncology, University Clinical Center Nis, Nis, Serbia., Stana M; Medical Oncology Department, 'Elysee Hospital', Alba Iulia, Romania., Ottonello S; Department of Experimental Medicine (DIMES), University of Genova, Genoa, Italy., Scavone G; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., de Moura Leite L; Department of Medical Oncology, A.C. Camargo Cancer Center, São Paulo, Brazil., Spinaci S; Department of Surgery, Ospedale di Villa Scassi ASL 3, Genoa, Italy., Saura C; Medical Oncology Service, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain., Lambertini M; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.
Source: European journal of clinical investigation [Eur J Clin Invest] 2025 Jun; Vol. 55 (6), pp. e70001. Date of Electronic Publication: 2025 Feb 13.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0245331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2362 (Electronic) Linking ISSN: 00142972 NLM ISO Abbreviation: Eur J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adverse events and impact on quality of life of antibody-drug conjugates in the treatment of metastatic breast cancer: A systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Perachino+M%22">Perachino M</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.; Medical Oncology Service, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blondeaux+E%22">Blondeaux E</searchLink>; U. O. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Molinelli+C%22">Molinelli C</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Ruelle+T%22">Ruelle T</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Giannubilo+I%22">Giannubilo I</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Arecco+L%22">Arecco L</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Nardin+S%22">Nardin S</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Razeti+MG%22">Razeti MG</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Borea+R%22">Borea R</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Favero+D%22">Favero D</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Lanzavecchia+C%22">Lanzavecchia C</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Chiappe+E%22">Chiappe E</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Tomasello+L%22">Tomasello L</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Section of Medical Oncology, Department of Precision Medicine in Medical, Surgical and Clinical Care (Me.Pre.C.C), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Mariamidze+E%22">Mariamidze E</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Oncology and Hematology Department, Todua Clinic, Tbilisi, Georgia.<br /><searchLink fieldCode="AU" term="%22Jankovic+K%22">Jankovic K</searchLink>; Clinic of Oncology, University Clinical Center Nis, Nis, Serbia.<br /><searchLink fieldCode="AU" term="%22Stana+M%22">Stana M</searchLink>; Medical Oncology Department, 'Elysee Hospital', Alba Iulia, Romania.<br /><searchLink fieldCode="AU" term="%22Ottonello+S%22">Ottonello S</searchLink>; Department of Experimental Medicine (DIMES), University of Genova, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Scavone+G%22">Scavone G</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22de+Moura+Leite+L%22">de Moura Leite L</searchLink>; Department of Medical Oncology, A.C. Camargo Cancer Center, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Spinaci+S%22">Spinaci S</searchLink>; Department of Surgery, Ospedale di Villa Scassi ASL 3, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Saura+C%22">Saura C</searchLink>; Medical Oncology Service, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lambertini+M%22">Lambertini M</searchLink>; U.O. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DiMI), School of Medicine, University of Genova, Genoa, Italy.
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  Data: <searchLink fieldCode="JN" term="%220245331%22">European journal of clinical investigation</searchLink> [Eur J Clin Invest] 2025 Jun; Vol. 55 (6), pp. e70001. <i>Date of Electronic Publication: </i>2025 Feb 13.
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