Applying positive end-expiratory pressure before and during endotracheal tube removal versus extubation with concomitant aspiration: protocol for the randomised controlled multicentre EXSUPEEP trial.

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Title: Applying positive end-expiratory pressure before and during endotracheal tube removal versus extubation with concomitant aspiration: protocol for the randomised controlled multicentre EXSUPEEP trial.
Authors: Sedillot N; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France nsedillot@ch-bourg01.fr., Kallel H; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France., Robine A; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France., Pineda JA; LabEx LipSTIC, Universite de Bourgogne, Dijon, Bourgogne-Franche-Comté, France.; Service de Médecine Intensive-Réanimation, CHU Dijon, Dijon, Bourgogne-Franche-Comté, France., Quenot JP; LabEx LipSTIC, Universite de Bourgogne, Dijon, Bourgogne-Franche-Comté, France.; Service de Médecine Intensive-Réanimation, CHU Dijon, Dijon, Bourgogne-Franche-Comté, France., Servant M; Réanimation médico-chirurgicale, Centre Hospitalier Annecy Genevois 1 Av. de l'Hôpital, 74370 Epagny Metz-Tessy, Annecy, France., Levrat A; Réanimation médico-chirurgicale, Centre Hospitalier Annecy Genevois 1 Av. de l'Hôpital, 74370 Epagny Metz-Tessy, Annecy, France., Damieux-Verdeau C; Service de Médecine Intensive-Réanimation Hôpital de la Croix Rousse, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Mezidi M; Service de Médecine Intensive-Réanimation Hôpital de la Croix Rousse, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Thibert N; Service de Réanimation Hôpital Lyon-sud, Pierre Benite, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Bohé J; Service de Réanimation Hôpital Lyon-sud, Pierre Benite, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Ballesteros-Calzado A; Service de Médecine Intensive Réanimation Hôpital Edouard Herriot, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Stevic N; Service de Médecine Intensive Réanimation Hôpital Edouard Herriot, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France., Mahi L; Service de Médecine Intensive Réanimation, CHU Grenoble Alpes, Grenoble, France., Sigaud F; Service de Médecine Intensive Réanimation, CHU Grenoble Alpes, Grenoble, France., Maisonneuve M; Service de Médecine Intensive et Réanimation, CHU de Saint-Étienne, Saint-Etienne, Auvergne-Rhône-Alpes, France., Thiery G; Service de Médecine Intensive et Réanimation, CHU de Saint-Étienne, Saint-Etienne, Auvergne-Rhône-Alpes, France., Prat P; Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France., Thille AW; Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France., Haouat S; Service de Réanimation Polyvalente, CH Argenteuil, Argenteuil, Île-de-France, France., Plantefeve G; Service de Réanimation Polyvalente, CH Argenteuil, Argenteuil, Île-de-France, France., Decullier E; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, Auvergne-Rhône-Alpes, France., Rabilloud M; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, Auvergne-Rhône-Alpes, France., Bernon P; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France., Poncelin Y; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France., Bonnici JC; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.
Source: BMJ open [BMJ Open] 2025 Feb 13; Vol. 15 (2), pp. e092354. Date of Electronic Publication: 2025 Feb 13.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: Applying positive end-expiratory pressure before and during endotracheal tube removal versus extubation with concomitant aspiration: protocol for the randomised controlled multicentre EXSUPEEP trial.
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  Data: <searchLink fieldCode="AU" term="%22Sedillot+N%22">Sedillot N</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France nsedillot@ch-bourg01.fr.<br /><searchLink fieldCode="AU" term="%22Kallel+H%22">Kallel H</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Robine+A%22">Robine A</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Pineda+JA%22">Pineda JA</searchLink>; LabEx LipSTIC, Universite de Bourgogne, Dijon, Bourgogne-Franche-Comté, France.; Service de Médecine Intensive-Réanimation, CHU Dijon, Dijon, Bourgogne-Franche-Comté, France.<br /><searchLink fieldCode="AU" term="%22Quenot+JP%22">Quenot JP</searchLink>; LabEx LipSTIC, Universite de Bourgogne, Dijon, Bourgogne-Franche-Comté, France.; Service de Médecine Intensive-Réanimation, CHU Dijon, Dijon, Bourgogne-Franche-Comté, France.<br /><searchLink fieldCode="AU" term="%22Servant+M%22">Servant M</searchLink>; Réanimation médico-chirurgicale, Centre Hospitalier Annecy Genevois 1 Av. de l'Hôpital, 74370 Epagny Metz-Tessy, Annecy, France.<br /><searchLink fieldCode="AU" term="%22Levrat+A%22">Levrat A</searchLink>; Réanimation médico-chirurgicale, Centre Hospitalier Annecy Genevois 1 Av. de l'Hôpital, 74370 Epagny Metz-Tessy, Annecy, France.<br /><searchLink fieldCode="AU" term="%22Damieux-Verdeau+C%22">Damieux-Verdeau C</searchLink>; Service de Médecine Intensive-Réanimation Hôpital de la Croix Rousse, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Mezidi+M%22">Mezidi M</searchLink>; Service de Médecine Intensive-Réanimation Hôpital de la Croix Rousse, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Thibert+N%22">Thibert N</searchLink>; Service de Réanimation Hôpital Lyon-sud, Pierre Benite, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Bohé+J%22">Bohé J</searchLink>; Service de Réanimation Hôpital Lyon-sud, Pierre Benite, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Ballesteros-Calzado+A%22">Ballesteros-Calzado A</searchLink>; Service de Médecine Intensive Réanimation Hôpital Edouard Herriot, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Stevic+N%22">Stevic N</searchLink>; Service de Médecine Intensive Réanimation Hôpital Edouard Herriot, CHU Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Mahi+L%22">Mahi L</searchLink>; Service de Médecine Intensive Réanimation, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Sigaud+F%22">Sigaud F</searchLink>; Service de Médecine Intensive Réanimation, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Maisonneuve+M%22">Maisonneuve M</searchLink>; Service de Médecine Intensive et Réanimation, CHU de Saint-Étienne, Saint-Etienne, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Thiery+G%22">Thiery G</searchLink>; Service de Médecine Intensive et Réanimation, CHU de Saint-Étienne, Saint-Etienne, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Prat+P%22">Prat P</searchLink>; Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Thille+AW%22">Thille AW</searchLink>; Service de Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Haouat+S%22">Haouat S</searchLink>; Service de Réanimation Polyvalente, CH Argenteuil, Argenteuil, Île-de-France, France.<br /><searchLink fieldCode="AU" term="%22Plantefeve+G%22">Plantefeve G</searchLink>; Service de Réanimation Polyvalente, CH Argenteuil, Argenteuil, Île-de-France, France.<br /><searchLink fieldCode="AU" term="%22Decullier+E%22">Decullier E</searchLink>; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Rabilloud+M%22">Rabilloud M</searchLink>; Pôle Santé Publique, Hospices Civils de Lyon, Lyon, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Bernon+P%22">Bernon P</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Poncelin+Y%22">Poncelin Y</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Bonnici+JC%22">Bonnici JC</searchLink>; Hôpital Fleyriat, Service de Réanimation Polyvalente, Centre Hospitalier de Bourg-en-Bresse, Bourg-en-Bresse, Rhône-Alpes, France.
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