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Variant-Specific Interactions at the Plasma Membrane: Heparan Sulfate's Impact on SARS-CoV-2 Binding Kinetics.

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Title: Variant-Specific Interactions at the Plasma Membrane: Heparan Sulfate's Impact on SARS-CoV-2 Binding Kinetics.
Authors: Conca DV; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Bano F; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Graul M; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., von Wirén J; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Scherrer L; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Pace H; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Sharma H; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå 901 87, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå 901 87, Sweden., Svirelis J; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden., Thorsteinsson K; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden., Dahlin A; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden., Bally M; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.
Source: Analytical chemistry [Anal Chem] 2025 Mar 04; Vol. 97 (8), pp. 4318-4328. Date of Electronic Publication: 2025 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Conca+DV%22">Conca DV</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Bano+F%22">Bano F</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Graul+M%22">Graul M</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22von+Wirén+J%22">von Wirén J</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Scherrer+L%22">Scherrer L</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Pace+H%22">Pace H</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Sharma+H%22">Sharma H</searchLink>; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.; Department of Medical Biochemistry and Biophysics, Umeå University, Umeå 901 87, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Svirelis+J%22">Svirelis J</searchLink>; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.<br /><searchLink fieldCode="AU" term="%22Thorsteinsson+K%22">Thorsteinsson K</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.<br /><searchLink fieldCode="AU" term="%22Dahlin+A%22">Dahlin A</searchLink>; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.<br /><searchLink fieldCode="AU" term="%22Bally+M%22">Bally M</searchLink>; Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden.; Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden.; Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå 901 87, Sweden.
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              Text: 2025 Mar 04
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