The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.

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Title: The MEK5/ERK5 pathway promotes the activation of the Hedgehog/GLI signaling in melanoma cells.
Authors: Tusa I; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy. ignazia.tusa@unifi.it., Gagliardi S; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy., Menconi A; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy., Maresca L; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy.; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy., Tubita A; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy., Lulli M; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy., Stecca B; Core Research Laboratory - Institute for Cancer Research and Prevention (ISPRO), Florence, Italy. b.stecca@ispro.toscana.it., Rovida E; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134, Florence, Italy. elisabetta.rovida@unifi.it.
Source: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2025 Jun; Vol. 48 (3), pp. 789-799. Date of Electronic Publication: 2025 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2211-3436
DOI:10.1007/s13402-025-01050-z