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Advancing age and sex modulate antidyskinetic efficacy of striatal CaV1.3 gene therapy in a rat model of Parkinson's disease.

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Title: Advancing age and sex modulate antidyskinetic efficacy of striatal CaV1.3 gene therapy in a rat model of Parkinson's disease.
Authors: Caulfield ME; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA., Vander Werp MJ; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA., Stancati JA; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA., Collier TJ; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA., Sortwell CE; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA., Sandoval IM; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Kordower JH; ASU-Banner Neurodegenerative Disease Research Center (NDRC), College of Liberal Arts and Sciences, Arizona State University, Tempe, AZ 85287, USA., Manfredsson FP; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA., Steece-Collier K; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA. Electronic address: collie68@msu.edu.
Source: Neurobiology of aging [Neurobiol Aging] 2025 May; Vol. 149, pp. 54-66. Date of Electronic Publication: 2025 Feb 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Advancing age and sex modulate antidyskinetic efficacy of striatal Ca<subscript>V</subscript>1.3 gene therapy in a rat model of Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Caulfield+ME%22">Caulfield ME</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Vander+Werp+MJ%22">Vander Werp MJ</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Stancati+JA%22">Stancati JA</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Collier+TJ%22">Collier TJ</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Sortwell+CE%22">Sortwell CE</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Sandoval+IM%22">Sandoval IM</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Kordower+JH%22">Kordower JH</searchLink>; ASU-Banner Neurodegenerative Disease Research Center (NDRC), College of Liberal Arts and Sciences, Arizona State University, Tempe, AZ 85287, USA.<br /><searchLink fieldCode="AU" term="%22Manfredsson+FP%22">Manfredsson FP</searchLink>; Parkinson's Disease Research Unit, Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ 85013, USA.<br /><searchLink fieldCode="AU" term="%22Steece-Collier+K%22">Steece-Collier K</searchLink>; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA. Electronic address: collie68@msu.edu.
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  Data: <searchLink fieldCode="JN" term="%228100437%22">Neurobiology of aging</searchLink> [Neurobiol Aging] 2025 May; Vol. 149, pp. 54-66. <i>Date of Electronic Publication: </i>2025 Feb 20.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8100437 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-1497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201974580%22">01974580 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Aging <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2025 May
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