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Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.

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Title: Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Authors: Wieteska Ł; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Faculty of Biological Sciences, Astbury Centre for Structural Studies, University of Leeds, Leeds, UK.; Developmental Signalling Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Taylor AB; Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Punch E; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Coleman JA; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Conway IO; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Lin YF; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada., Byeon CH; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Hinck CS; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Krzysiak T; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Ishima R; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., López-Casillas F; Departmento de Biología Celular y del Desarrollo, Instituto de Fisiología Celular, UNAM, Mexico City, Mexico., Cherepanov P; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, NW1 1AT, UK., Bernard DJ; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada., Hill CS; Developmental Signalling Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. caroline.hill@crick.ac.uk., Hinck AP; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA. ahinck@pitt.edu.
Source: Nature communications [Nat Commun] 2025 Feb 26; Vol. 16 (1), pp. 1778. Date of Electronic Publication: 2025 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
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  Data: <searchLink fieldCode="AU" term="%22Wieteska+Ł%22">Wieteska Ł</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Faculty of Biological Sciences, Astbury Centre for Structural Studies, University of Leeds, Leeds, UK.; Developmental Signalling Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Taylor+AB%22">Taylor AB</searchLink>; Department of Biochemistry & Structural Biology and Greehey Children's Cancer Research Institute, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Punch+E%22">Punch E</searchLink>; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Coleman+JA%22">Coleman JA</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Conway+IO%22">Conway IO</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lin+YF%22">Lin YF</searchLink>; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Byeon+CH%22">Byeon CH</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hinck+CS%22">Hinck CS</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Krzysiak+T%22">Krzysiak T</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ishima+R%22">Ishima R</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22López-Casillas+F%22">López-Casillas F</searchLink>; Departmento de Biología Celular y del Desarrollo, Instituto de Fisiología Celular, UNAM, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Cherepanov+P%22">Cherepanov P</searchLink>; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Bernard+DJ%22">Bernard DJ</searchLink>; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Hill+CS%22">Hill CS</searchLink>; Developmental Signalling Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. caroline.hill@crick.ac.uk.<br /><searchLink fieldCode="AU" term="%22Hinck+AP%22">Hinck AP</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA. ahinck@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Feb 26; Vol. 16 (1), pp. 1778. <i>Date of Electronic Publication: </i>2025 Feb 26.
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