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The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan.

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Title: The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan.
Authors: Shimose S; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan. shimose_shigeo@med.kurume-u.ac.jp., Saeki I; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Ito T; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Takeuchi Y; Department of Gastroenterology, Okayama University Hospital, Okayama, Japan., Tani J; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu, Japan., Tomonari T; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan., Sasaki R; Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Sasaki K; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan., Kakizaki S; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan., Hatanaka T; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Iwamoto H; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.; Iwamoto Internal Medical Clinic, Kitakyusyu, Japan., Tanabe N; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Yamamoto T; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Naganuma A; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan., Shirono T; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan., Kanayama Y; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Nishina S; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan., Takayama T; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan., Kobara H; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu, Japan., Otsuka M; Department of Gastroenterology, Okayama University Hospital, Okayama, Japan., Kawashima H; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Takami T; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Kawaguchi T; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
Corporate Authors: representing the Hepatology InVestigator Experts in Japan (HIVE-J) Study Group
Source: Hepatology international [Hepatol Int] 2025 Aug; Vol. 19 (4), pp. 846-855. Date of Electronic Publication: 2025 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101304009 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-0541 (Electronic) Linking ISSN: 19360533 NLM ISO Abbreviation: Hepatol Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan.
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  Data: <searchLink fieldCode="AU" term="%22Shimose+S%22">Shimose S</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan. shimose_shigeo@med.kurume-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Saeki+I%22">Saeki I</searchLink>; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+T%22">Ito T</searchLink>; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+Y%22">Takeuchi Y</searchLink>; Department of Gastroenterology, Okayama University Hospital, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Tani+J%22">Tani J</searchLink>; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Tomonari+T%22">Tomonari T</searchLink>; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Sasaki+R%22">Sasaki R</searchLink>; Department of Gastroenterology and Hepatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Sasaki+K%22">Sasaki K</searchLink>; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Kakizaki+S%22">Kakizaki S</searchLink>; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan.<br /><searchLink fieldCode="AU" term="%22Hatanaka+T%22">Hatanaka T</searchLink>; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan.<br /><searchLink fieldCode="AU" term="%22Iwamoto+H%22">Iwamoto H</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.; Iwamoto Internal Medical Clinic, Kitakyusyu, Japan.<br /><searchLink fieldCode="AU" term="%22Tanabe+N%22">Tanabe N</searchLink>; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+T%22">Yamamoto T</searchLink>; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Naganuma+A%22">Naganuma A</searchLink>; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan.<br /><searchLink fieldCode="AU" term="%22Shirono+T%22">Shirono T</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.<br /><searchLink fieldCode="AU" term="%22Kanayama+Y%22">Kanayama Y</searchLink>; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan.<br /><searchLink fieldCode="AU" term="%22Nishina+S%22">Nishina S</searchLink>; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Takayama+T%22">Takayama T</searchLink>; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan.<br /><searchLink fieldCode="AU" term="%22Kobara+H%22">Kobara H</searchLink>; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Takamatsu, Japan.<br /><searchLink fieldCode="AU" term="%22Otsuka+M%22">Otsuka M</searchLink>; Department of Gastroenterology, Okayama University Hospital, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kawashima+H%22">Kawashima H</searchLink>; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Takami+T%22">Takami T</searchLink>; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.<br /><searchLink fieldCode="AU" term="%22Kawaguchi+T%22">Kawaguchi T</searchLink>; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan.
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