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Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.

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Title: Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.
Authors: Kim J; Division of Quantitative and Clinical Sciences, Department of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN, USA.; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Williams A; Center for Precision Health Research, National Human Genome Research Institute, National Institute of Health, Bethesda, MD, USA., Noh H; Tufts University Medical School Graduate Programs, Boston, MA, USA.; Medicine, Health and Society, Vanderbilt University, Nashville, TN, USA., Jasper EA; Division of Quantitative and Clinical Sciences, Department of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Jones SH; Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA., Jaworski JA; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Shuey MM; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ruiz-Narváez EA; Department of Nutritional Sciences University of Michigan School of Public Health, Ann Arbor, MI, USA., Wise LA; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Palmer JR; Slone Epidemiology Center at Boston University, Boston, MA, USA., Connolly J; Center for Applied Genomics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Keaton JM; Center for Precision Health Research, National Human Genome Research Institute, National Institute of Health, Bethesda, MD, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Denny JC; Center for Precision Health Research, National Human Genome Research Institute, National Institute of Health, Bethesda, MD, USA.; All of Us Research Program, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Khan A; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA., Abbass MA; Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Rasmussen-Torvik LJ; Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Kottyan LC; Center for Autoimmune Genomics and Etiology, Department of Pediatrics, Cincinnati Children's Hospital, University of Cincinnati, Cincinnati, OH, USA., Madhivanan P; University of Arizona Comprehensive Cancer Center, Tucson, AZ, USA.; Department of Health Promotion Sciences, Mel & Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.; Public Health Research Institute of India, Mysuru, India.; Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA., Krupp K; University of Arizona Comprehensive Cancer Center, Tucson, AZ, USA.; Public Health Research Institute of India, Mysuru, India.; Public Health Practice, Policy, & Translational Research Department, Mel & Enid Zuckerman College of Public Health, Phoenix, AZ, USA., Wei WQ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Velez Edwards DR; Division of Quantitative and Clinical Sciences, Department of Obstetrics & Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org.; Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org.; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA. digna.r.velez.edwards@vumc.org., Hellwege JN; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. jacklyn.hellwege@vumc.org.; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA. jacklyn.hellwege@vumc.org.; Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA. jacklyn.hellwege@vumc.org.
Source: Nature communications [Nat Commun] 2025 Mar 06; Vol. 16 (1), pp. 2273. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.
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