Reduced removal of waste products from energy metabolism takes center stage in human brain aging.
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| Title: | Reduced removal of waste products from energy metabolism takes center stage in human brain aging. |
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| Authors: | Mangia S; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, USA. mangia@umn.edu., DiNuzzo M; Netabolics SRL, Rome, RM, Italy., Ponticorvo S; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, USA., Dienel GA; Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Behar KL; Department of Psychiatry, Yale University, School of Medicine, New Haven, CT, USA., Benveniste H; Department of Anesthesiology, Yale University, New Haven, CT, USA.; Department of Biomedical Engineering, Yale University, New Haven, CT, USA., Hyder F; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.; Department of Radiology, Magnetic Resonance Research Center (MRRC), Yale University, New Haven, CT, USA., Giove F; Centro Ricerche Enrico Fermi, Rome, RM, Italy.; Fondazione Santa Lucia IRCCS, Rome, RM, Italy., Herculano-Houzel S; Department of Psychology, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA., Petroff OA; Department of Neurology, Yale University, School of Medicine, New Haven, CT, USA., Eberly LE; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, USA.; Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Filip P; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, USA.; Department of Neurology, First Faculty of Medicine and General University Hospital, 121 08, Prague, Czech Republic., Michaeli S; Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, MN, USA., Rothman DL; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.; Department of Radiology, Magnetic Resonance Research Center (MRRC), Yale University, New Haven, CT, USA. |
| Source: | Scientific reports [Sci Rep] 2025 Mar 08; Vol. 15 (1), pp. 8127. Date of Electronic Publication: 2025 Mar 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-90342-3 |
