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High Mortality Due to Pneumococcal Meningitis in Children With Sickle Cell Disease: A French Multicenter Observational Study From 2001 to 2021.

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Title: High Mortality Due to Pneumococcal Meningitis in Children With Sickle Cell Disease: A French Multicenter Observational Study From 2001 to 2021.
Authors: Fafi I; From the Pediatrics Department, Jean Verdier Hospital, Assistance Publique-Hôpitaux de Paris, Bondy, France., Cohen R; Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, Ile-de-France, France.; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France.; Groupe de Recherche Clinique-Groupe d'Etude des Maladies Infectieuses Néonatales et Infantiles, Institut Mondor de Recherche Biomédicale, Université Paris Est, Créteil, France., Levy C; Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, Ile-de-France, France.; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France.; Groupe de Recherche Clinique-Groupe d'Etude des Maladies Infectieuses Néonatales et Infantiles, Institut Mondor de Recherche Biomédicale, Université Paris Est, Créteil, France., Varon E; National Reference Center for Pneumococci, Créteil, France., Amor-Chelihi L; From the Pediatrics Department, Jean Verdier Hospital, Assistance Publique-Hôpitaux de Paris, Bondy, France.; Sickle-cell Disease Center, Jean Verdier Hospital, University hospital Paris Seine-Saint-Denis, Assistance Publique-Hôpitaux de Paris, Bondy, France., Benhaim P; Pediatrics Department, Trousseau Hospital, Paris, France., Houlier M; Pediatrics Department, Trousseau Hospital, Paris, France., Koehl B; Université Paris Cité, INSERM, Biologie intégrée du globule rouge, Paris, France.; Sickle Cell Disease Center, Hematology Unit, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, Paris, France., De Montalembert M; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France., Allali S; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France., Gauthier A; Laboratory LIBM EA7424, Vascular Biology and Red Blood Cell Team, University of Lyon, Lyon, France.; Institut d'Hématologie et d'Oncologique Pédiatrique, Hospices Civils de Lyon, Lyon, France., Odièvre MH; Pediatrics Department, Trousseau Hospital, Paris, France., Gajdos V; General Pediatrics Department, Antoine-Béclère Hospital-Assistance Publique-Hôpitaux de Paris, Paris Saclay University, Clamart, France., Escoda S; General Pediatrics Department, Delafontaine Hospital, Saint-Denis, France., Kamdem A; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France., Costa G; Department of Pediatrics, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, Corbeil-Essonnes, France., Guillaumat C; Department of Pediatrics, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, Corbeil-Essonnes, France., Thuret I; Sickle-cell disease Center, Hematology Department, Hôpital La Timone Enfants, Assistance Publique Hôpitaux de Marseille, Marseille, France., Ouldali N; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Department of General Pediatrics, Pediatric Infectious Disease and Internal Medicine, Robert Debré University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France., Gaschignard J; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France.; Department of Paediatrics, Groupe Hospitalier Nord Essonne, Longjumeau, France., Carbonnelle E; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France.; Microbiology department, Avicenne Hospital, University hospital Paris Seine-Saint-Denis, Assistance Publique-Hôpitaux de Paris, Bobigny, France., De Pontual L; Pediatrics Department, Trousseau Hospital, Paris, France., Pham LL; Pediatrics Department, Trousseau Hospital, Paris, France.
Source: The Pediatric infectious disease journal [Pediatr Infect Dis J] 2025 Jun 01; Vol. 44 (6), pp. 496-502. Date of Electronic Publication: 2025 Mar 07.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Williams & Wilkins Country of Publication: United States NLM ID: 8701858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-0987 (Electronic) Linking ISSN: 08913668 NLM ISO Abbreviation: Pediatr Infect Dis J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High Mortality Due to Pneumococcal Meningitis in Children With Sickle Cell Disease: A French Multicenter Observational Study From 2001 to 2021.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Fafi+I%22">Fafi I</searchLink>; From the Pediatrics Department, Jean Verdier Hospital, Assistance Publique-Hôpitaux de Paris, Bondy, France.<br /><searchLink fieldCode="AU" term="%22Cohen+R%22">Cohen R</searchLink>; Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, Ile-de-France, France.; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France.; Groupe de Recherche Clinique-Groupe d'Etude des Maladies Infectieuses Néonatales et Infantiles, Institut Mondor de Recherche Biomédicale, Université Paris Est, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Levy+C%22">Levy C</searchLink>; Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, Ile-de-France, France.; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France.; Groupe de Recherche Clinique-Groupe d'Etude des Maladies Infectieuses Néonatales et Infantiles, Institut Mondor de Recherche Biomédicale, Université Paris Est, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Varon+E%22">Varon E</searchLink>; National Reference Center for Pneumococci, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Amor-Chelihi+L%22">Amor-Chelihi L</searchLink>; From the Pediatrics Department, Jean Verdier Hospital, Assistance Publique-Hôpitaux de Paris, Bondy, France.; Sickle-cell Disease Center, Jean Verdier Hospital, University hospital Paris Seine-Saint-Denis, Assistance Publique-Hôpitaux de Paris, Bondy, France.<br /><searchLink fieldCode="AU" term="%22Benhaim+P%22">Benhaim P</searchLink>; Pediatrics Department, Trousseau Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Houlier+M%22">Houlier M</searchLink>; Pediatrics Department, Trousseau Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Koehl+B%22">Koehl B</searchLink>; Université Paris Cité, INSERM, Biologie intégrée du globule rouge, Paris, France.; Sickle Cell Disease Center, Hematology Unit, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22De+Montalembert+M%22">De Montalembert M</searchLink>; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Allali+S%22">Allali S</searchLink>; Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gauthier+A%22">Gauthier A</searchLink>; Laboratory LIBM EA7424, Vascular Biology and Red Blood Cell Team, University of Lyon, Lyon, France.; Institut d'Hématologie et d'Oncologique Pédiatrique, Hospices Civils de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Odièvre+MH%22">Odièvre MH</searchLink>; Pediatrics Department, Trousseau Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gajdos+V%22">Gajdos V</searchLink>; General Pediatrics Department, Antoine-Béclère Hospital-Assistance Publique-Hôpitaux de Paris, Paris Saclay University, Clamart, France.<br /><searchLink fieldCode="AU" term="%22Escoda+S%22">Escoda S</searchLink>; General Pediatrics Department, Delafontaine Hospital, Saint-Denis, France.<br /><searchLink fieldCode="AU" term="%22Kamdem+A%22">Kamdem A</searchLink>; Research Center, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Costa+G%22">Costa G</searchLink>; Department of Pediatrics, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, Corbeil-Essonnes, France.<br /><searchLink fieldCode="AU" term="%22Guillaumat+C%22">Guillaumat C</searchLink>; Department of Pediatrics, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, Corbeil-Essonnes, France.<br /><searchLink fieldCode="AU" term="%22Thuret+I%22">Thuret I</searchLink>; Sickle-cell disease Center, Hematology Department, Hôpital La Timone Enfants, Assistance Publique Hôpitaux de Marseille, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Ouldali+N%22">Ouldali N</searchLink>; Groupe de Pathologie Infectieuse Pédiatrique, Paris, France.; Department of General Pediatrics, Pediatric Infectious Disease and Internal Medicine, Robert Debré University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gaschignard+J%22">Gaschignard J</searchLink>; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France.; Department of Paediatrics, Groupe Hospitalier Nord Essonne, Longjumeau, France.<br /><searchLink fieldCode="AU" term="%22Carbonnelle+E%22">Carbonnelle E</searchLink>; INSERM UMR 1137, Infection, Antimicrobials, Modelling, Evolution, Paris Cité University, Paris, France.; Microbiology department, Avicenne Hospital, University hospital Paris Seine-Saint-Denis, Assistance Publique-Hôpitaux de Paris, Bobigny, France.<br /><searchLink fieldCode="AU" term="%22De+Pontual+L%22">De Pontual L</searchLink>; Pediatrics Department, Trousseau Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pham+LL%22">Pham LL</searchLink>; Pediatrics Department, Trousseau Hospital, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%228701858%22">The Pediatric infectious disease journal</searchLink> [Pediatr Infect Dis J] 2025 Jun 01; Vol. 44 (6), pp. 496-502. <i>Date of Electronic Publication: </i>2025 Mar 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Williams+%26+Wilkins%22">Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8701858 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-0987 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208913668%22">08913668 </searchLink><i>NLM ISO Abbreviation: </i>Pediatr Infect Dis J <i>Subsets: </i>MEDLINE
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