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The CRISPR-Cas9 System Is Used to Edit the Autoimmune Regulator Gene in Vitro and in Vivo.

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Title: The CRISPR-Cas9 System Is Used to Edit the Autoimmune Regulator Gene in Vitro and in Vivo.
Authors: Tanaka PP; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Monteiro CJ; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Duarte MJ; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Oliveira ED; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Monteleone-Cassiano AC; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.; Program in Basic and Applied Immunology, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil., Mascarenhas RS; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Vieira Machado MC; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Matos AA; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Brito LA; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Oliveira AO; Cryopreservation Laboratory, Central Animal Facility, USP, Ribeirão Preto, SP, Brazil., Cunha TM; Center for Research in Inflammatory Diseases (CRID), Department of Pharmacology, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil., Donadi EA; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil., Passos GA; Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, Ribeirão Preto School of Dentistry (FORP-USP), University of São Paulo, Ribeirão Preto, SP, Brazil. passos@usp.br.
Source: Advances in experimental medicine and biology [Adv Exp Med Biol] 2025; Vol. 1471, pp. 269-283.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Tanaka+PP%22">Tanaka PP</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Monteiro+CJ%22">Monteiro CJ</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Duarte+MJ%22">Duarte MJ</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+ED%22">Oliveira ED</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Monteleone-Cassiano+AC%22">Monteleone-Cassiano AC</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.; Program in Basic and Applied Immunology, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Mascarenhas+RS%22">Mascarenhas RS</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Vieira+Machado+MC%22">Vieira Machado MC</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Matos+AA%22">Matos AA</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Brito+LA%22">Brito LA</searchLink>; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+AO%22">Oliveira AO</searchLink>; Cryopreservation Laboratory, Central Animal Facility, USP, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Cunha+TM%22">Cunha TM</searchLink>; Center for Research in Inflammatory Diseases (CRID), Department of Pharmacology, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Donadi+EA%22">Donadi EA</searchLink>; Division of Clinical Immunology, Department of Clinical Medicine, Ribeirão Preto Medical School, USP, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Passos+GA%22">Passos GA</searchLink>; Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, Ribeirão Preto School of Dentistry (FORP-USP), University of São Paulo, Ribeirão Preto, SP, Brazil. passos@usp.br.
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