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Pharmacokinetics of betamethasone in pre-eclampsia: An in vivo and ex vivo study.

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Title: Pharmacokinetics of betamethasone in pre-eclampsia: An in vivo and ex vivo study.
Authors: Schoenmakers S; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands., Li L; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands., Kluivers ACM; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands., Broekhuizen M; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Harhangi MS; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Danser AHJ; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands., Reiss I; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Allegaert K; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.; Leuven Child and Youth Institute, KU Leuven, Leuven, Belgium., van den Berg SAA; Department of Internal Medicine, Division of Endocrinology, Erasmus University Medical Center, the Netherlands.; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands., van Zelst BD; Department of Internal Medicine, Division of Endocrinology, Erasmus University Medical Center, the Netherlands., van Schaik RHN; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands., DeKoninck PLJ; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands., Ronde E; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands., Sassen SDT; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Center for Antimicrobial Treatment Optimization Rotterdam (CATOR), the Netherlands.; Rotterdam Clinical Pharmacometrics Group, Rotterdam, the Netherlands., Simons SHP; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands., Koch BCP; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Center for Antimicrobial Treatment Optimization Rotterdam (CATOR), the Netherlands.; Rotterdam Clinical Pharmacometrics Group, Rotterdam, the Netherlands.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Aug; Vol. 91 (8), pp. 2327-2339. Date of Electronic Publication: 2025 Mar 13.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacokinetics of betamethasone in pre-eclampsia: An in vivo and ex vivo study.
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  Data: <searchLink fieldCode="AU" term="%22Schoenmakers+S%22">Schoenmakers S</searchLink>; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kluivers+ACM%22">Kluivers ACM</searchLink>; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Broekhuizen+M%22">Broekhuizen M</searchLink>; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Harhangi+MS%22">Harhangi MS</searchLink>; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Danser+AHJ%22">Danser AHJ</searchLink>; Department of Internal Medicine, Division of Pharmacology and Vascular Medicine, Erasmus MC University Hospital, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Reiss+I%22">Reiss I</searchLink>; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Allegaert+K%22">Allegaert K</searchLink>; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.; Leuven Child and Youth Institute, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22van+den+Berg+SAA%22">van den Berg SAA</searchLink>; Department of Internal Medicine, Division of Endocrinology, Erasmus University Medical Center, the Netherlands.; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Zelst+BD%22">van Zelst BD</searchLink>; Department of Internal Medicine, Division of Endocrinology, Erasmus University Medical Center, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Schaik+RHN%22">van Schaik RHN</searchLink>; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22DeKoninck+PLJ%22">DeKoninck PLJ</searchLink>; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ronde+E%22">Ronde E</searchLink>; Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sassen+SDT%22">Sassen SDT</searchLink>; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Center for Antimicrobial Treatment Optimization Rotterdam (CATOR), the Netherlands.; Rotterdam Clinical Pharmacometrics Group, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Simons+SHP%22">Simons SHP</searchLink>; Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koch+BCP%22">Koch BCP</searchLink>; Department of Hospital Pharmacy, Erasmus University Medical Center, The Netherlands.; Center for Antimicrobial Treatment Optimization Rotterdam (CATOR), the Netherlands.; Rotterdam Clinical Pharmacometrics Group, Rotterdam, the Netherlands.
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