Polygenic risk scores for rheumatoid arthritis and idiopathic pulmonary fibrosis and associations with RA, interstitial lung abnormalities, and quantitative interstitial abnormalities among smokers.

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Title: Polygenic risk scores for rheumatoid arthritis and idiopathic pulmonary fibrosis and associations with RA, interstitial lung abnormalities, and quantitative interstitial abnormalities among smokers.
Authors: McDermott GC; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Moll M; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Pulmonary, Allergy, Sleep and Critical Care Medicine Section, Department of Medicine, VA Boston Healthcare System, West Roxbury, MA, USA., Cho MH; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hayashi K; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA., Juge PA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Université de Paris Cité, INSERM UMR 1152, F-75018 Paris, France; Service de Rhumatologie, Hôpital Bichat-Claude Bernard, AP-HP, F-75018 Paris, France., Doyle TJ; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Paudel ML; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Kinney GL; Colorado School of Public Health, Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Kronzer VL; Division of Rheumatology, Mayo Clinic, Rochester, MN, USA., Kim JS; Division of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, VA, USA., O'Keeffe LA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA., Davis NA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA., Bernstein EJ; Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Dellaripa PF; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Regan EA; Division of Rheumatology, National Jewish Health, Denver, CO, USA., Hunninghake GM; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Silverman EK; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Ash SY; Division of Pulmonary and Critical Care Medicine, South Shore Health, South Weymouth, MA, USA., San Jose Estepar R; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Washko GR; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Sparks JA; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: jsparks@bwh.harvard.edu.
Source: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2025 Jun; Vol. 72, pp. 152708. Date of Electronic Publication: 2025 Mar 15.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 1306053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-866X (Electronic) Linking ISSN: 00490172 NLM ISO Abbreviation: Semin Arthritis Rheum Subsets: MEDLINE
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  Data: Polygenic risk scores for rheumatoid arthritis and idiopathic pulmonary fibrosis and associations with RA, interstitial lung abnormalities, and quantitative interstitial abnormalities among smokers.
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  Data: <searchLink fieldCode="AU" term="%22McDermott+GC%22">McDermott GC</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Moll+M%22">Moll M</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Pulmonary, Allergy, Sleep and Critical Care Medicine Section, Department of Medicine, VA Boston Healthcare System, West Roxbury, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cho+MH%22">Cho MH</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hayashi+K%22">Hayashi K</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Juge+PA%22">Juge PA</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Université de Paris Cité, INSERM UMR 1152, F-75018 Paris, France; Service de Rhumatologie, Hôpital Bichat-Claude Bernard, AP-HP, F-75018 Paris, France.<br /><searchLink fieldCode="AU" term="%22Doyle+TJ%22">Doyle TJ</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Paudel+ML%22">Paudel ML</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kinney+GL%22">Kinney GL</searchLink>; Colorado School of Public Health, Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Kronzer+VL%22">Kronzer VL</searchLink>; Division of Rheumatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Kim+JS%22">Kim JS</searchLink>; Division of Pulmonary and Critical Care Medicine, University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22O'Keeffe+LA%22">O'Keeffe LA</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Davis+NA%22">Davis NA</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+EJ%22">Bernstein EJ</searchLink>; Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dellaripa+PF%22">Dellaripa PF</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Regan+EA%22">Regan EA</searchLink>; Division of Rheumatology, National Jewish Health, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Hunninghake+GM%22">Hunninghake GM</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Silverman+EK%22">Silverman EK</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ash+SY%22">Ash SY</searchLink>; Division of Pulmonary and Critical Care Medicine, South Shore Health, South Weymouth, MA, USA.<br /><searchLink fieldCode="AU" term="%22San+Jose+Estepar+R%22">San Jose Estepar R</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Washko+GR%22">Washko GR</searchLink>; Harvard Medical School, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sparks+JA%22">Sparks JA</searchLink>; Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: jsparks@bwh.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%221306053%22">Seminars in arthritis and rheumatism</searchLink> [Semin Arthritis Rheum] 2025 Jun; Vol. 72, pp. 152708. <i>Date of Electronic Publication: </i>2025 Mar 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1306053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-866X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200490172%22">00490172 </searchLink><i>NLM ISO Abbreviation: </i>Semin Arthritis Rheum <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.semarthrit.2025.152708
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