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Supercharging CAR-T cells through transcriptional and epigenetic armoring.

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Title: Supercharging CAR-T cells through transcriptional and epigenetic armoring.
Authors: Qin D; Cancer Center, Clinical Trial Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore., Lei Y; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Shu P; Division of Abdominal Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Zhang Y; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Loh YH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore., Wang Y; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Cancer Center, National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Li Q; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore.; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
Source: Theranostics [Theranostics] 2025 Feb 18; Vol. 15 (8), pp. 3345-3367. Date of Electronic Publication: 2025 Feb 18 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Supercharging CAR-T cells through transcriptional and epigenetic armoring.
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  Data: <searchLink fieldCode="AU" term="%22Qin+D%22">Qin D</searchLink>; Cancer Center, Clinical Trial Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Shu+P%22">Shu P</searchLink>; Division of Abdominal Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Loh+YH%22">Loh YH</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Cancer Center, National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs, West China Hospital, Sichuan University, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A ∗ STAR), Singapore 138673, Singapore.; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2025 Feb 18; Vol. 15 (8), pp. 3345-3367. <i>Date of Electronic Publication: </i>2025 Feb 18 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE
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        Value: 10.7150/thno.107908
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        Text: English
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      – TitleFull: Supercharging CAR-T cells through transcriptional and epigenetic armoring.
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              Text: 2025 Feb 18
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