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Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial.

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Title: Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial.
Authors: Jabaudon M; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Quenot JP; The Lipness Team, INSERM Lipids, Nutrition, Cancer-Unité Mixte de Recherche 1231 and LabEx LipSTIC, INSERM Centre d'Investigation Clinique 1432, Clinical Epidemiology, Université de Bourgogne, and Médecine Intensive Réanimation, CHU Dijon, Dijon, France., Badie J; Réanimation Polyvalente, Hôpital Nord Franche-Comté, Trévenans, France., Audard J; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France., Jaber S; Centre Hospitalier Universitaire (CHU) Montpellier, Département Anesthésie Réanimation B, Hôpital Saint Eloi and PhyMedExp, INSERM U1046, Université de Montpellier, Montpellier, France., Rieu B; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France., Varillon C; Department of Medical Intensive Care, Dunkerque Hospital, 59240 Dunkerque, France., Monsel A; Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care, La Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), and INSERM UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Biotherapy (CIC-BTi), Sorbonne University, Paris, France., Thouy F; Réanimation Médicale Polyvalente, CHU Gabriel Montpied, Clermont-Ferrand, France., Lorber J; Department of Intensive Care Medicine, Hospital of Saint-Nazaire, Saint-Nazaire, France., Cousson J; Department of Critical Care Medicine, University Hospital (CHU) of Reims, Reims, France., Bulyez S; Department of Anesthesiology, Pain, and Critical Care Medicine, Carémeau Hospital, University Hospital (CHU) of Nîmes, Nîmes, France., Bourenne J; Department of Intensive Care Medicine, Timone Hospital, Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France., Sboui G; Department of Intensive Care Medicine, Hospital of Béthune, Béthune, France., Lhommet C; Department of Anesthesiology and Critical Care Medicine, Diaconesses-La Croix Simon Hospital, Paris, France., Lemiale V; Department of Intensive Care Medicine, Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Bouhemad B; Department of Anesthesiology and Critical Care Medicine, University Hospital (CHU) of Dijon and the Lipness Team, INSERM UMR1231, Dijon, France., Brault C; Department of Intensive Care Medicine, University Hospital (CHU) of Amiens, Amiens, France., Lasocki S; Department of Anesthesiology and Critical Care Medicine, University Hospital (CHU) of Angers, Angers, France., Legay F; Department of Intensive Care Medicine, Hospital of Saint-Brieuc, Saint-Brieuc, France., Lebouvier T; Department of Anesthesiology and Critical Care Medicine, University Hospital (CHU) of Rennes, Rennes, France., Durand A; Department of Critical Care Medicine, Salengro Hospital, University Hospital (CHU) of Lille, Lille, France., Pottecher J; Department of Anesthesiology and Critical Care Medicine, Hautepierre Hospital, University Hospital (CHU) and UR3072, FHU Omicare, FHU Data-Surge, FMTS, Strasbourg University, Strasbourg, France., Conia A; Department of Intensive Care Medicine, Hospital of Chartres, Chartres, France., Brégeaud D; Department of Intensive Care Medicine, Hospital of Saintes, Saintes, France., Velly L; Department of Anesthesiology and Critical Care Medicine, Timone Hospital, Assistance Publique-Hôpitaux de Marseille and Institut des Neurosciences de la Timone, CNRS, Aix Marseille University, Marseille, France., Thille AW; Department of Intensive Care Medicine, University Hospital of Poitiers, Poitiers, France., Lambiotte F; Department of Intensive Care Medicine, Hospital of Valenciennes, Valenciennes, France., L'Her E; Department of Intensive Care Medicine, Cavale Blanche University Hospital (CHU) and Laboratoire de Traitement de l'Information Médicale, Unité Mixte de Recherche 1101, INSERM, Université de Bretagne Occidentale, Brest, France., Monchi M; Department of Intensive Care Medicine, Hospital of Melun-Sénart, Melun, France., Roquilly A; University of Nantes, CHU Nantes, Department of Anesthesiology and Intensive Care Unit, CIC Immunology and Infection, and INSERM UMR 1064 CR2TI, Nantes, France., Berrouba A; Department of Critical Care Medicine, Hospital of Martigues, Martigues, France., Verdonk F; Department of Anesthesiology and Intensive Care, Hôpital Saint-Antoine and Hôpital Tenon, GRC 29, DMU DREAM, Assistance Publique-Hôpitaux de Paris (AP-HP) and UMRS 938, Centre de Recherche Saint-Antoine (CRSA), Sorbonne Université, INSERM, Paris, France., Chabanne R; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France., Godet T; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; Department of Healthcare Simulation and NEURO-DOL, UMR 1107, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Garnier M; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Blondonnet R; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Vernhes J; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France., Sapin V; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France.; Department of Biochemistry and Molecular Genetics, CHU Clermont-Ferrand, Clermont-Ferrand, France., Borao L; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France., Futier E; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France., Pereira B; Biostatistics and Data Management Unit, Department of Clinical Research and Innovation, CHU Clermont-Ferrand, Clermont-Ferrand, France., Constantin JM; Sorbonne University, GRC 29, AP-HP, DMU DREAM, Department of Anesthesiology and Critical Care, Pitié-Salpêtrière Hospital, Paris, France.
Corporate Authors: SESAR Trial Investigators
Source: JAMA [JAMA] 2025 May 13; Vol. 333 (18), pp. 1608-1617.
Publication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Jabaudon+M%22">Jabaudon M</searchLink>; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.; iGReD, CNRS, INSERM, Université Clermont Auvergne, Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Quenot+JP%22">Quenot JP</searchLink>; The Lipness Team, INSERM Lipids, Nutrition, Cancer-Unité Mixte de Recherche 1231 and LabEx LipSTIC, INSERM Centre d'Investigation Clinique 1432, Clinical Epidemiology, Université de Bourgogne, and Médecine Intensive Réanimation, CHU Dijon, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Badie+J%22">Badie J</searchLink>; Réanimation Polyvalente, Hôpital Nord Franche-Comté, Trévenans, France.<br /><searchLink fieldCode="AU" term="%22Audard+J%22">Audard J</searchLink>; Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Jaber+S%22">Jaber S</searchLink>; Centre Hospitalier Universitaire (CHU) Montpellier, Département Anesthésie Réanimation B, Hôpital Saint Eloi and PhyMedExp, INSERM U1046, Université de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Rieu+B%22">Rieu B</searchLink>; 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Department of Critical Care Medicine, University Hospital (CHU) of Reims, Reims, France.<br /><searchLink fieldCode="AU" term="%22Bulyez+S%22">Bulyez S</searchLink>; Department of Anesthesiology, Pain, and Critical Care Medicine, Carémeau Hospital, University Hospital (CHU) of Nîmes, Nîmes, France.<br /><searchLink fieldCode="AU" term="%22Bourenne+J%22">Bourenne J</searchLink>; Department of Intensive Care Medicine, Timone Hospital, Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France.<br /><searchLink fieldCode="AU" term="%22Sboui+G%22">Sboui G</searchLink>; Department of Intensive Care Medicine, Hospital of Béthune, Béthune, France.<br /><searchLink fieldCode="AU" term="%22Lhommet+C%22">Lhommet C</searchLink>; Department of Anesthesiology and Critical Care Medicine, Diaconesses-La Croix Simon Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lemiale+V%22">Lemiale V</searchLink>; Department of Intensive Care Medicine, Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.<br /><searchLink fieldCode="AU" term="%22Bouhemad+B%22">Bouhemad B</searchLink>; 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          Titles:
            – TitleFull: JAMA
              Type: main
ResultId 1