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Obesity promotes immunotherapy efficacy by up-regulating the glycolytic-mediated histone lactacylation modification of CD8+ T cells.

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Title: Obesity promotes immunotherapy efficacy by up-regulating the glycolytic-mediated histone lactacylation modification of CD8+ T cells.
Authors: Wang KX; Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Shi DM; Department of Medical Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China., Shi XL; Department of General Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China., Wang JY; Department of Medical Oncology, Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Ai XH; Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Mar 05; Vol. 16, pp. 1533464. Date of Electronic Publication: 2025 Mar 05 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wang+KX%22">Wang KX</searchLink>; Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shi+DM%22">Shi DM</searchLink>; Department of Medical Oncology, Changzheng Hospital, Naval Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shi+XL%22">Shi XL</searchLink>; Department of General Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wang+JY%22">Wang JY</searchLink>; Department of Medical Oncology, Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ai+XH%22">Ai XH</searchLink>; Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2025 Mar 05; Vol. 16, pp. 1533464. <i>Date of Electronic Publication: </i>2025 Mar 05 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fphar.2025.1533464
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        Text: English
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            – D: 05
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              Text: 2025 Mar 05
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