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Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma.

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Title: Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma.
Authors: Ding YF; Department of Otolaryngology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Otolaryngology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC., Ho KH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC., Lee WJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Medical Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC., Chen LH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC., Hsieh FK; The Genome Engineering & Stem Cell Center, School of Medicine, Washington University, St. Louis, MO, USA., Tung MC; Department of Surgery, Tungs' Taichung Metro Harbor Hospital, Taichung, Taiwan, ROC., Lin SH; Department of Surgical Pathology, Changhua Christian Hospital, Changhua, Taiwan, ROC.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan, ROC., Hsiao M; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC., Yang YC; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC. ycyang@tmu.edu.tw.; School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan, ROC. ycyang@tmu.edu.tw.; Department of Medical Research, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan, ROC. ycyang@tmu.edu.tw., Chien MH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; TMU Research Center for Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; Traditional Herbal Medicine Research Center, Taipei Medical University Hospital Taipei, Taipei, Taiwan, ROC. mhchien1976@gmail.com.
Source: Cell death & disease [Cell Death Dis] 2025 Mar 20; Vol. 16 (1), pp. 191. Date of Electronic Publication: 2025 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Ding+YF%22">Ding YF</searchLink>; Department of Otolaryngology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Otolaryngology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ho+KH%22">Ho KH</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lee+WJ%22">Lee WJ</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.; Department of Medical Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+LH%22">Chen LH</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsieh+FK%22">Hsieh FK</searchLink>; The Genome Engineering & Stem Cell Center, School of Medicine, Washington University, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Tung+MC%22">Tung MC</searchLink>; Department of Surgery, Tungs' Taichung Metro Harbor Hospital, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+SH%22">Lin SH</searchLink>; Department of Surgical Pathology, Changhua Christian Hospital, Changhua, Taiwan, ROC.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsiao+M%22">Hsiao M</searchLink>; Genomics Research Center, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yang+SF%22">Yang SF</searchLink>; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yang+YC%22">Yang YC</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC. ycyang@tmu.edu.tw.; School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan, ROC. ycyang@tmu.edu.tw.; Department of Medical Research, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan, ROC. ycyang@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chien+MH%22">Chien MH</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; TMU Research Center for Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, ROC. mhchien1976@gmail.com.; Traditional Herbal Medicine Research Center, Taipei Medical University Hospital Taipei, Taipei, Taiwan, ROC. mhchien1976@gmail.com.
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              Text: 2025 Mar 20
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