Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells.

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Title: Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells.
Authors: Labaf M; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Mathematics, University of Massachusetts Boston, Boston, Massachusetts.; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Han W; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.; Human Biology Division, Fred Hutchinson Cancer Center, Washington., Zhang S; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Liu M; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Patten ND; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Li M; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.; Division of Urology, Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Patalano S; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Macoska JA; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Balk SP; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Han D; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts., Zarringhalam K; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Cai C; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2025 May 02; Vol. 24 (5), pp. 772-783.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
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  Data: Heterogeneous Responses to High-Dose Testosterone in Castration-Resistant Prostate Cancer Tumors with Mixed Rb-Proficient and Rb-Deficient Cells.
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  Data: <searchLink fieldCode="AU" term="%22Labaf+M%22">Labaf M</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Mathematics, University of Massachusetts Boston, Boston, Massachusetts.; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Han+W%22">Han W</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.; Human Biology Division, Fred Hutchinson Cancer Center, Washington.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Patten+ND%22">Patten ND</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.; Division of Urology, Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Patalano+S%22">Patalano S</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Macoska+JA%22">Macoska JA</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Balk+SP%22">Balk SP</searchLink>; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Han+D%22">Han D</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zarringhalam+K%22">Zarringhalam K</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Cai+C%22">Cai C</searchLink>; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts.; Department of Biology, University of Massachusetts Boston, Boston, Massachusetts.
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