6,7-Dimethoxy-2-methyl-4-substituted quinazolines: Design, synthesis, EGFR inhibitory activity, in vitro cytotoxicity, and in silico studies.
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| Title: | 6,7-Dimethoxy-2-methyl-4-substituted quinazolines: Design, synthesis, EGFR inhibitory activity, in vitro cytotoxicity, and in silico studies. |
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| Authors: | Saleh NS; Egyptian Drug Authority (EDA), 51 Wezaret El-Zeraa St., Giza, 35521, Egypt., El-Sayed NNE; Egyptian Drug Authority (EDA), 51 Wezaret El-Zeraa St., Giza, 35521, Egypt., Saleh OA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical Industries Research Institute, National Research Centre, Egypt., Allam HA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, P.O. Box 11562, Kasr El-Aini Street, Cairo, Egypt., Mohamed NM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Modern University for Technology and Information MTI, Cairo, Egypt., Abbas SE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, P.O. Box 11562, Kasr El-Aini Street, Cairo, Egypt., Said MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, P.O. Box 11562, Kasr El-Aini Street, Cairo, Egypt. Electronic address: mona.abdelnoor@pharma.cu.edu.eg. |
| Source: | European journal of medicinal chemistry [Eur J Med Chem] 2025 Jun 05; Vol. 290, pp. 117502. Date of Electronic Publication: 2025 Mar 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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