Inhibition of human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer.
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| Title: | Inhibition of human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer. |
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| Authors: | Nakagawa T; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA. tanakagawa@health.ucsd.edu.; Department of Otorhinolaryngology, Head and Neck Surgery, Chiba University, Graduate School of Medicine, Chiba, Japan. tanakagawa@health.ucsd.edu.; Health and Disease Omics Center, Chiba University, Chiba, Japan. tanakagawa@health.ucsd.edu., Luebeck J; Department of Computer Science and Engineering, UC San Diego, La Jolla, CA, USA., Zhu K; Department of Computer Science and Engineering, UC San Diego, La Jolla, CA, USA., Lange JT; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Sasik R; Center for Computational Biology and Bioinformatics, University of California, San Diego, La Jolla, CA, USA., Phillips C; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Sadat S; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Javadzadeh S; Department of Computer Science and Engineering, UC San Diego, La Jolla, CA, USA., Yang Q; Department of Cellular and Molecular Medicine, Center for Epigenomics, University of California, San Diego, La Jolla, CA, USA., Monther A; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Fassardi S; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Wang A; Department of Cellular and Molecular Medicine, Center for Epigenomics, University of California, San Diego, La Jolla, CA, USA., Pestonjamasp K; Cancer Center Microscopy Core, University of California, San Diego, La Jolla, CA, USA., Rosenthal B; Center for Computational Biology and Bioinformatics, University of California, San Diego, La Jolla, CA, USA., Fisch KM; Center for Computational Biology and Bioinformatics, University of California, San Diego, La Jolla, CA, USA., Mischel P; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Bafna V; Department of Computer Science and Engineering, UC San Diego, La Jolla, CA, USA., Califano JA; Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA. jcalifano@health.ucsd.edu.; Department of Otolaryngology-Head and Neck Surgery and Gleiberman Head and Neck Cancer Center, University of California, San Diego, La Jolla, CA, USA. jcalifano@health.ucsd.edu. |
| Source: | Nature communications [Nat Commun] 2025 Mar 26; Vol. 16 (1), pp. 2964. Date of Electronic Publication: 2025 Mar 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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