Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.
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| Title: | Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures. |
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| Authors: | Scialò C; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Zhong W; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Jagannath S; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Wilkins O; UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK; The Francis Crick Institute, London, UK., Caredio D; Institute of Neuropathology, University of Zurich, Zurich, Switzerland., Hruska-Plochan M; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Lurati F; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., Peter M; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., De Cecco E; Institute of Neuropathology, University of Zurich, Zurich, Switzerland., Celauro L; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy., Aguzzi A; Institute of Neuropathology, University of Zurich, Zurich, Switzerland., Legname G; Laboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy., Fratta P; UCL Queen Square Motor Neuron Disease Centre, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, UCL, London, UK; The Francis Crick Institute, London, UK., Polymenidou M; Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland. Electronic address: magdalini.polymenidou@uzh.ch. |
| Source: | Neuron [Neuron] 2025 May 21; Vol. 113 (10), pp. 1614-1628.e11. Date of Electronic Publication: 2025 Mar 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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