View in EDS

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.

Saved in:
Bibliographic Details
Title: ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.
Authors: Jenkins BJ; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Jenkins YR; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Ponce-Garcia FM; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Moscrop C; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK., Perry IA; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Hitchings MD; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Uribe AH; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Bernuzzi F; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Eastham S; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK., Cronin JG; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Berisha A; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland., Howell A; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK., Davies J; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK., Blagih J; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; University of Montreal, Maisonneuve-Rosemont Hospital Research Centre, Montreal, 5414 Assomption Blvd, H1T 2M4, Canada., Veale DJ; EULAR Centre of Excellence, Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin, Ireland., Davies LC; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK., Niphakis M; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Finlay DK; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearce Street, Dublin, Ireland., Sinclair LV; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK., Cravatt BF; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States., Hogan AE; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland., Nathan JA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, CB2 0AW, UK., Fearon U; Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearce Street, Dublin, Ireland., Sumpton D; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Vande Voorde J; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; School of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow, G61 1QH, UK., Dias do Vale G; Center for Human Nutrition, Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States., McDonald JG; Center for Human Nutrition, Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States., Jones GW; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK., Pearson JA; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK., Vincent EE; School of Translational Health Sciences, Dorothy Hodgkin Building, University of Bristol, Bristol, BS1 3NY, UK.; Integrative Epidemiology Unit, School of Population Health Science, University of Bristol, Bristol, BS8 2BN, UK., Jones N; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 19. Date of Electronic Publication: 2025 Mar 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40166327
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jenkins+BJ%22">Jenkins BJ</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Jenkins+YR%22">Jenkins YR</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Ponce-Garcia+FM%22">Ponce-Garcia FM</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Moscrop+C%22">Moscrop C</searchLink>; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Perry+IA%22">Perry IA</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Hitchings+MD%22">Hitchings MD</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Uribe+AH%22">Uribe AH</searchLink>; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Bernuzzi+F%22">Bernuzzi F</searchLink>; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Eastham+S%22">Eastham S</searchLink>; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Cronin+JG%22">Cronin JG</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Berisha+A%22">Berisha A</searchLink>; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.<br /><searchLink fieldCode="AU" term="%22Howell+A%22">Howell A</searchLink>; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Davies+J%22">Davies J</searchLink>; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Blagih+J%22">Blagih J</searchLink>; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.; University of Montreal, Maisonneuve-Rosemont Hospital Research Centre, Montreal, 5414 Assomption Blvd, H1T 2M4, Canada.<br /><searchLink fieldCode="AU" term="%22Veale+DJ%22">Veale DJ</searchLink>; EULAR Centre of Excellence, Centre for Arthritis and Rheumatic Diseases, St Vincent's University Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Davies+LC%22">Davies LC</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.<br /><searchLink fieldCode="AU" term="%22Niphakis+M%22">Niphakis M</searchLink>; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.<br /><searchLink fieldCode="AU" term="%22Finlay+DK%22">Finlay DK</searchLink>; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearce Street, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Sinclair+LV%22">Sinclair LV</searchLink>; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Cravatt+BF%22">Cravatt BF</searchLink>; Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.<br /><searchLink fieldCode="AU" term="%22Hogan+AE%22">Hogan AE</searchLink>; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.<br /><searchLink fieldCode="AU" term="%22Nathan+JA%22">Nathan JA</searchLink>; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, CB2 0AW, UK.<br /><searchLink fieldCode="AU" term="%22Fearon+U%22">Fearon U</searchLink>; Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152-160 Pearce Street, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Sumpton+D%22">Sumpton D</searchLink>; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Vande+Voorde+J%22">Vande Voorde J</searchLink>; Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; School of Cancer Sciences, Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Dias+do+Vale+G%22">Dias do Vale G</searchLink>; Center for Human Nutrition, Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.<br /><searchLink fieldCode="AU" term="%22McDonald+JG%22">McDonald JG</searchLink>; Center for Human Nutrition, Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.<br /><searchLink fieldCode="AU" term="%22Jones+GW%22">Jones GW</searchLink>; Cellular and Molecular Medicine, University of Bristol, Biomedical Sciences Building, Bristol, BS8 1TD, UK.<br /><searchLink fieldCode="AU" term="%22Pearson+JA%22">Pearson JA</searchLink>; Diabetes Research Group, Division of Infection and Immunity, School of Medicine, Cardiff University, CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Vincent+EE%22">Vincent EE</searchLink>; School of Translational Health Sciences, Dorothy Hodgkin Building, University of Bristol, Bristol, BS1 3NY, UK.; Integrative Epidemiology Unit, School of Population Health Science, University of Bristol, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Jones+N%22">Jones N</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea University, SA2 8PP, UK.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Mar 19. <i>Date of Electronic Publication: </i>2025 Mar 19.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40166327
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1101/2025.03.19.643996
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jenkins BJ
      – PersonEntity:
          Name:
            NameFull: Jenkins YR
      – PersonEntity:
          Name:
            NameFull: Ponce-Garcia FM
      – PersonEntity:
          Name:
            NameFull: Moscrop C
      – PersonEntity:
          Name:
            NameFull: Perry IA
      – PersonEntity:
          Name:
            NameFull: Hitchings MD
      – PersonEntity:
          Name:
            NameFull: Uribe AH
      – PersonEntity:
          Name:
            NameFull: Bernuzzi F
      – PersonEntity:
          Name:
            NameFull: Eastham S
      – PersonEntity:
          Name:
            NameFull: Cronin JG
      – PersonEntity:
          Name:
            NameFull: Berisha A
      – PersonEntity:
          Name:
            NameFull: Howell A
      – PersonEntity:
          Name:
            NameFull: Davies J
      – PersonEntity:
          Name:
            NameFull: Blagih J
      – PersonEntity:
          Name:
            NameFull: Veale DJ
      – PersonEntity:
          Name:
            NameFull: Davies LC
      – PersonEntity:
          Name:
            NameFull: Niphakis M
      – PersonEntity:
          Name:
            NameFull: Finlay DK
      – PersonEntity:
          Name:
            NameFull: Sinclair LV
      – PersonEntity:
          Name:
            NameFull: Cravatt BF
      – PersonEntity:
          Name:
            NameFull: Hogan AE
      – PersonEntity:
          Name:
            NameFull: Nathan JA
      – PersonEntity:
          Name:
            NameFull: Fearon U
      – PersonEntity:
          Name:
            NameFull: Sumpton D
      – PersonEntity:
          Name:
            NameFull: Vande Voorde J
      – PersonEntity:
          Name:
            NameFull: Dias do Vale G
      – PersonEntity:
          Name:
            NameFull: McDonald JG
      – PersonEntity:
          Name:
            NameFull: Jones GW
      – PersonEntity:
          Name:
            NameFull: Pearson JA
      – PersonEntity:
          Name:
            NameFull: Vincent EE
      – PersonEntity:
          Name:
            NameFull: Jones N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 19
              M: 03
              Text: 2025 Mar 19
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1