An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis.

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Title: An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis.
Authors: Hu T; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Zheng Q; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Cao C; College of Pharmaceutical Sciences, Southwest University, Chongqing, China., Li S; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Huang Y; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Guan Z; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Ji L; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Bing J; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Du H; Institutes of Biomedical Sciences, Fudan University, Shanghai, China., Perry AM; Department of Molecular and Cell Biology, University of California, Merced, California, United States of America.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, United States of America., Nobile CJ; Department of Molecular and Cell Biology, University of California, Merced, California, United States of America.; Health Sciences Research Institute, University of California, Merced, California, United States of America., Li B; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China., Chu H; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China., Huang G; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.; College of Pharmaceutical Sciences, Southwest University, Chongqing, China.
Source: PLoS biology [PLoS Biol] 2025 Apr 01; Vol. 23 (4), pp. e3003062. Date of Electronic Publication: 2025 Apr 01 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
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  Data: An agricultural triazole induces genomic instability and haploid cell formation in the human fungal pathogen Candida tropicalis.
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  Data: <searchLink fieldCode="AU" term="%22Hu+T%22">Hu T</searchLink>; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Q%22">Zheng Q</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Cao+C%22">Cao C</searchLink>; College of Pharmaceutical Sciences, Southwest University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guan+Z%22">Guan Z</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ji+L%22">Ji L</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bing+J%22">Bing J</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Du+H%22">Du H</searchLink>; Institutes of Biomedical Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Perry+AM%22">Perry AM</searchLink>; Department of Molecular and Cell Biology, University of California, Merced, California, United States of America.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Nobile+CJ%22">Nobile CJ</searchLink>; Department of Molecular and Cell Biology, University of California, Merced, California, United States of America.; Health Sciences Research Institute, University of California, Merced, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chu+H%22">Chu H</searchLink>; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.; Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+G%22">Huang G</searchLink>; Department of infectious diseases, Huashan Hospital, Shanghai Institute of Infectious Disease and Biosecurity and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.; College of Pharmaceutical Sciences, Southwest University, Chongqing, China.
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