Acetylshikonin induces cell necroptosis via mediating mitochondrial function and oxidative stress-regulated signaling in human Oral Cancer cells.
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| Title: | Acetylshikonin induces cell necroptosis via mediating mitochondrial function and oxidative stress-regulated signaling in human Oral Cancer cells. |
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| Authors: | Shao KY; Oral-Maxillofacial Surgery Division, Department of Dentistry, Shuang Ho Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan., Luo SD; Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Taiwan; School of Traditional Chinese Medicine, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan; School of Medicine, College of Medicine, National SunYat-sen University, Kaohsiung, Taiwan., Huang EY; Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung City, Taiwan; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung City, Taiwan., Chang TM; School of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan., Botcha L; Institute of Biomedical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan., Sehar M; Institute of Biomedical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan., Liu JF; School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: jufangliu@tmu.edu.tw., Chuang PK; Institute of Biomedical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan. Electronic address: pkchuang@mail.nsysu.edu.tw. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2025 Jun 01; Vol. 159, pp. 108396. Date of Electronic Publication: 2025 Mar 21. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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