Effect of FcRn Binding on Monoclonal Antibody Disposition in the Brain.

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Title: Effect of FcRn Binding on Monoclonal Antibody Disposition in the Brain.
Authors: Huang HW; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, the State University of New York, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA., Wu S; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, the State University of New York, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA., Liu S; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, the State University of New York, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA., Shah DK; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, the State University of New York, 455 Pharmacy Building, Buffalo, New York, 14214-8033, USA. dshah4@buffalo.edu.
Source: The AAPS journal [AAPS J] 2025 Apr 01; Vol. 27 (3), pp. 72. Date of Electronic Publication: 2025 Apr 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1550-7416
DOI:10.1208/s12248-025-01060-7