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Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder.

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Title: Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder.
Authors: Nishi Y; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Toritsuka M; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan. michihiro.toritsuka@fujita-hu.ac.jp.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. michihiro.toritsuka@fujita-hu.ac.jp.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. michihiro.toritsuka@fujita-hu.ac.jp., Takada R; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Ishikawa M; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan., Ishida R; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan., Kayashima Y; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Yamauchi T; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Okumura K; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Takeda T; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan., Yamamuro K; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Center for Health Control, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Ikehara M; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Noriyama Y; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Kamikawa K; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan., Murayama S; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan., Ichikawa O; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan., Nagata H; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan., Okano H; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Keio University Regenerative Medicine Research Center Research Gate Building TONOMACHI 2-4F, 3-25-10 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan., Iwata N; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan., Makinodan M; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan. manabu.makinodan@fujita-hu.ac.jp.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. manabu.makinodan@fujita-hu.ac.jp.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. manabu.makinodan@fujita-hu.ac.jp.
Source: Molecular psychiatry [Mol Psychiatry] 2025 Aug; Vol. 30 (8), pp. 3837-3845. Date of Electronic Publication: 2025 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder.
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  Data: <searchLink fieldCode="AU" term="%22Nishi+Y%22">Nishi Y</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Toritsuka+M%22">Toritsuka M</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan. michihiro.toritsuka@fujita-hu.ac.jp.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. michihiro.toritsuka@fujita-hu.ac.jp.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. michihiro.toritsuka@fujita-hu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Takada+R%22">Takada R</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Ishikawa+M%22">Ishikawa M</searchLink>; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Ishida+R%22">Ishida R</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Kayashima+Y%22">Kayashima Y</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Yamauchi+T%22">Yamauchi T</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Okumura+K%22">Okumura K</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Takeda+T%22">Takeda T</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamuro+K%22">Yamamuro K</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.; Center for Health Control, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Ikehara+M%22">Ikehara M</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Noriyama+Y%22">Noriyama Y</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Kamikawa+K%22">Kamikawa K</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan.<br /><searchLink fieldCode="AU" term="%22Murayama+S%22">Murayama S</searchLink>; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan.<br /><searchLink fieldCode="AU" term="%22Ichikawa+O%22">Ichikawa O</searchLink>; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan.<br /><searchLink fieldCode="AU" term="%22Nagata+H%22">Nagata H</searchLink>; Research and Development, Sumitomo Pharma Co., Ltd., Osaka city, Osaka, 554-0022, Japan.<br /><searchLink fieldCode="AU" term="%22Okano+H%22">Okano H</searchLink>; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.; Keio University Regenerative Medicine Research Center Research Gate Building TONOMACHI 2-4F, 3-25-10 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-0821, Japan.<br /><searchLink fieldCode="AU" term="%22Iwata+N%22">Iwata N</searchLink>; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Makinodan+M%22">Makinodan M</searchLink>; Department of Psychiatry, Nara Medical University School of Medicine, Kashihara, Nara, 634-8522, Japan. manabu.makinodan@fujita-hu.ac.jp.; Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. manabu.makinodan@fujita-hu.ac.jp.; Division of Transformative Psychiatry and Synergistic Research, International Center for Brain Science (ICBS), Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan. manabu.makinodan@fujita-hu.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2025 Aug; Vol. 30 (8), pp. 3837-3845. <i>Date of Electronic Publication: </i>2025 Apr 04.
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              Text: 2025 Aug
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