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Interactions Between Direct Oral Anticoagulants and Drugs Involving CYP-Enzymes and P-gp Transporters Detected by a Clinical Decision Support System: A Retrospective Cohort Study.

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Title: Interactions Between Direct Oral Anticoagulants and Drugs Involving CYP-Enzymes and P-gp Transporters Detected by a Clinical Decision Support System: A Retrospective Cohort Study.
Authors: Wuyts SCM; Pharmacy Department, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium. stephanie.wuyts@vub.be.; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium. stephanie.wuyts@vub.be., Bonte S; Faculty of Pharmacy and Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium., Thielemans N; Department of Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium., Vandervorst F; Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.; NEUR Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium., von Kemp B; Department of Cardiology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium., Steurbaut S; Pharmacy Department, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.; Vitality Research Group, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 190, Belgium., Dupont AG; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium., Cornu P; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.; Department of Information and Communication Technology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
Source: Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2026 Feb; Vol. 40 (1), pp. 225-239. Date of Electronic Publication: 2025 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy Country of Publication: United States NLM ID: 8712220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7241 (Electronic) Linking ISSN: 09203206 NLM ISO Abbreviation: Cardiovasc Drugs Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interactions Between Direct Oral Anticoagulants and Drugs Involving CYP-Enzymes and P-gp Transporters Detected by a Clinical Decision Support System: A Retrospective Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Wuyts+SCM%22">Wuyts SCM</searchLink>; Pharmacy Department, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium. stephanie.wuyts@vub.be.; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium. stephanie.wuyts@vub.be.<br /><searchLink fieldCode="AU" term="%22Bonte+S%22">Bonte S</searchLink>; Faculty of Pharmacy and Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.<br /><searchLink fieldCode="AU" term="%22Thielemans+N%22">Thielemans N</searchLink>; Department of Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.<br /><searchLink fieldCode="AU" term="%22Vandervorst+F%22">Vandervorst F</searchLink>; Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.; NEUR Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.<br /><searchLink fieldCode="AU" term="%22von+Kemp+B%22">von Kemp B</searchLink>; Department of Cardiology, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.<br /><searchLink fieldCode="AU" term="%22Steurbaut+S%22">Steurbaut S</searchLink>; Pharmacy Department, Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, Brussels, 1090, Belgium.; Vitality Research Group, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 190, Belgium.<br /><searchLink fieldCode="AU" term="%22Dupont+AG%22">Dupont AG</searchLink>; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.<br /><searchLink fieldCode="AU" term="%22Cornu+P%22">Cornu P</searchLink>; Research Centre for Digital Medicine, Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, 1090, Belgium.; Department of Information and Communication Technology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.
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  Data: <searchLink fieldCode="JN" term="%228712220%22">Cardiovascular drugs and therapy</searchLink> [Cardiovasc Drugs Ther] 2026 Feb; Vol. 40 (1), pp. 225-239. <i>Date of Electronic Publication: </i>2025 Apr 08.
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              Text: 2026 Feb
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