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Guiding clinical management of patients with CNS lymphomas by minimal-invasive detection of ctDNA in cerebrospinal fluid.

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Title: Guiding clinical management of patients with CNS lymphomas by minimal-invasive detection of ctDNA in cerebrospinal fluid.
Authors: Weinschenk S; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Philipp U; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kuehn JC; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany., Mueller K; Department of Neurology, University Hospital, LMU Munich, Munich, Germany., Fauser J; Department of Internal Medicine V (Hematology and Oncology), Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria., Boeckle D; Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Benjamin Franklin, University Medical Center Berlin, Berlin, Germany., Gebhard I; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hinz M; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Neidert N; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany., Bleul S; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lauer EM; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Mutter JA; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA, USA., Alig SK; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA, USA.; Department of Internal Medicine III, Ludwig-Maximilians-University (LMU) Hospital, Munich, Germany., Kurtz DM; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA, USA., Finke J; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Marks R; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Diehn M; Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA., Alizadeh AA; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA, USA., Reinacher PC; Department of Stereotactic and Functional Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Fraunhofer Institute for Laser Technology (ILT), Aachen, Germany., Wehrle J; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Keller U; Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Benjamin Franklin, University Medical Center Berlin, Berlin, Germany.; German Cancer Consortium (DKTK) partner site Charité Berlin and German Cancer Research Center (DKFZ), Heidelberg, Germany., Wolf D; Department of Internal Medicine V (Hematology and Oncology), Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria., Kocher F; Department of Internal Medicine V (Hematology and Oncology), Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria., Chapuy B; Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Benjamin Franklin, University Medical Center Berlin, Berlin, Germany.; German Cancer Consortium (DKTK) partner site Charité Berlin and German Cancer Research Center (DKFZ), Heidelberg, Germany., Beck J; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany., Prinz M; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., von Baumgarten L; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK) partner site Munich and German Cancer Research Center (DKFZ), Heidelberg, Germany., Schorb E; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Duyster J; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Scherer F; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. florian.scherer@uniklinik-freiburg.de.; German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany. florian.scherer@uniklinik-freiburg.de.
Source: Leukemia [Leukemia] 2025 May; Vol. 39 (5), pp. 1265-1268. Date of Electronic Publication: 2025 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE; In Process
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Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Diehn+M%22">Diehn M</searchLink>; Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alizadeh+AA%22">Alizadeh AA</searchLink>; Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reinacher+PC%22">Reinacher PC</searchLink>; Department of Stereotactic and Functional Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Fraunhofer Institute for Laser Technology (ILT), Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Wehrle+J%22">Wehrle J</searchLink>; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Keller+U%22">Keller U</searchLink>; Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Benjamin Franklin, University Medical Center Berlin, Berlin, Germany.; German Cancer Consortium (DKTK) partner site Charité Berlin and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wolf+D%22">Wolf D</searchLink>; Department of Internal Medicine V (Hematology and Oncology), Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Kocher+F%22">Kocher F</searchLink>; Department of Internal Medicine V (Hematology and Oncology), Comprehensive Cancer Center Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Chapuy+B%22">Chapuy B</searchLink>; Department of Hematology, Oncology, and Tumor Immunology, Charité, Campus Benjamin Franklin, University Medical Center Berlin, Berlin, Germany.; German Cancer Consortium (DKTK) partner site Charité Berlin and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Beck+J%22">Beck J</searchLink>; Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Prinz+M%22">Prinz M</searchLink>; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Baumgarten+L%22">von Baumgarten L</searchLink>; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.; Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK) partner site Munich and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schorb+E%22">Schorb E</searchLink>; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Duyster+J%22">Duyster J</searchLink>; 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