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Improved antibody breadth with an extended primary dose interval of COVID-19 vaccine is overcome by boosters.

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Title: Improved antibody breadth with an extended primary dose interval of COVID-19 vaccine is overcome by boosters.
Authors: Ahmed JI; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Krosta SJ; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Reimer MN; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Cheung W; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Mesa C; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Lopez C; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Chua RJ; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Alsattari F; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Robinson A; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada., Manguiat K; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada., Jahan N; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., Abrenica B; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Harris A; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Cachero K; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Fabia R; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Walker J; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Oo MM; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., Stein D; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.; Department of Serology and Parasitology, Cadham Provincial Laboratory, Winnipeg, MB, Canada., Ji H; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., Su RC; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., McLaren PJ; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., McKinnon LR; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.; Department of Serology and Parasitology, Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa., Ball TB; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., Wood H; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada., Kim J; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada., Kiazyk SA; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada., Card CM; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.
Source: Frontiers in immunology [Front Immunol] 2025 Mar 27; Vol. 16, pp. 1529134. Date of Electronic Publication: 2025 Mar 27 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Improved antibody breadth with an extended primary dose interval of COVID-19 vaccine is overcome by boosters.
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  Data: <searchLink fieldCode="AU" term="%22Ahmed+JI%22">Ahmed JI</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Krosta+SJ%22">Krosta SJ</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Reimer+MN%22">Reimer MN</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Cheung+W%22">Cheung W</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Mesa+C%22">Mesa C</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Lopez+C%22">Lopez C</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Chua+RJ%22">Chua RJ</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Alsattari+F%22">Alsattari F</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Robinson+A%22">Robinson A</searchLink>; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Manguiat+K%22">Manguiat K</searchLink>; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Jahan+N%22">Jahan N</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Abrenica+B%22">Abrenica B</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Harris+A%22">Harris A</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Cachero+K%22">Cachero K</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Fabia+R%22">Fabia R</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Walker+J%22">Walker J</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Oo+MM%22">Oo MM</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Stein+D%22">Stein D</searchLink>; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.; Department of Serology and Parasitology, Cadham Provincial Laboratory, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Ji+H%22">Ji H</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Su+RC%22">Su RC</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22McLaren+PJ%22">McLaren PJ</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22McKinnon+LR%22">McKinnon LR</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.; Department of Serology and Parasitology, Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Ball+TB%22">Ball TB</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Wood+H%22">Wood H</searchLink>; Division of Mycobacteriology, Vector-borne and Prion Diseases, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Kiazyk+SA%22">Kiazyk SA</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Card+CM%22">Card CM</searchLink>; Division of Sexually-Transmitted and Blood-Borne Infections, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Mar 27; Vol. 16, pp. 1529134. <i>Date of Electronic Publication: </i>2025 Mar 27 (<i>Print Publication: </i>2025).
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