ALVAC-prime and monomeric gp120 protein boost induces distinct HIV-1 specific humoral and cellular responses compared with adenovirus-prime and trimeric gp140 protein boost.

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Title: ALVAC-prime and monomeric gp120 protein boost induces distinct HIV-1 specific humoral and cellular responses compared with adenovirus-prime and trimeric gp140 protein boost.
Authors: Fisher LH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Lazarus E; Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Yu C; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Moodie Z; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Stieh DJ; Janssen Vaccines & Prevention, Leiden, The Netherlands., Yates N; Duke Human Vaccine Institute, Duke University, Durham, North Carolina, United States of America., Zhang L; Duke University, Durham, North Carolina, United States of America., Sawant S; Duke University, Durham, North Carolina, United States of America., De Rosa SC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Cohen KW; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Morris D; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Grant S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Randhawa A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Miner MD; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Hendriks J; Janssen Vaccines & Prevention, Leiden, The Netherlands., Wegmann F; Janssen Vaccines & Prevention, Leiden, The Netherlands., Gill KM; The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa., Laher F; Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Soweto, South Africa., Bekker LG; The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa., Gray GE; South African Medical Research Council, Cape Town, South Africa., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Martin T; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Gilbert PB; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America., Tomaras G; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America., Walsh SR; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America., Baden LR; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
Corporate Authors: HVTN 100, HVTN 117/HPX2004 study teams
Source: PLOS global public health [PLOS Glob Public Health] 2025 Apr 11; Vol. 5 (4), pp. e0004250. Date of Electronic Publication: 2025 Apr 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 9918283779606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-3375 (Electronic) Linking ISSN: 27673375 NLM ISO Abbreviation: PLOS Glob Public Health Subsets: PubMed not MEDLINE
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  Data: ALVAC-prime and monomeric gp120 protein boost induces distinct HIV-1 specific humoral and cellular responses compared with adenovirus-prime and trimeric gp140 protein boost.
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  Data: <searchLink fieldCode="AU" term="%22Fisher+LH%22">Fisher LH</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Lazarus+E%22">Lazarus E</searchLink>; Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Moodie+Z%22">Moodie Z</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Stieh+DJ%22">Stieh DJ</searchLink>; Janssen Vaccines & Prevention, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yates+N%22">Yates N</searchLink>; Duke Human Vaccine Institute, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Sawant+S%22">Sawant S</searchLink>; Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22De+Rosa+SC%22">De Rosa SC</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Cohen+KW%22">Cohen KW</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Morris+D%22">Morris D</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Grant+S%22">Grant S</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Randhawa+A%22">Randhawa A</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Miner+MD%22">Miner MD</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Hendriks+J%22">Hendriks J</searchLink>; Janssen Vaccines & Prevention, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wegmann+F%22">Wegmann F</searchLink>; Janssen Vaccines & Prevention, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gill+KM%22">Gill KM</searchLink>; The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Laher+F%22">Laher F</searchLink>; Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Soweto, South Africa.<br /><searchLink fieldCode="AU" term="%22Bekker+LG%22">Bekker LG</searchLink>; The Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Gray+GE%22">Gray GE</searchLink>; South African Medical Research Council, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Corey+L%22">Corey L</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22McElrath+MJ%22">McElrath MJ</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Martin+T%22">Martin T</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Gilbert+PB%22">Gilbert PB</searchLink>; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Biostatistics, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Tomaras+G%22">Tomaras G</searchLink>; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America.; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Walsh+SR%22">Walsh SR</searchLink>; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Baden+LR%22">Baden LR</searchLink>; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
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  Data: <searchLink fieldCode="CA" term="%22HVTN+100%2C+HVTN+117%2FHPX2004+study+teams%22">HVTN 100, HVTN 117/HPX2004 study teams</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229918283779606676%22">PLOS global public health</searchLink> [PLOS Glob Public Health] 2025 Apr 11; Vol. 5 (4), pp. e0004250. <i>Date of Electronic Publication: </i>2025 Apr 11 (<i>Print Publication: </i>2025).
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