Astrocytic RNA editing regulates the host immune response to alpha-synuclein.
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| Title: | Astrocytic RNA editing regulates the host immune response to alpha-synuclein. |
|---|---|
| Authors: | D'Sa K; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Choi ML; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Brain & Cognitive Sciences, KAIST, 921 Dehak-ro, Daejeon, Republic of Korea., Wagen AZ; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Setó-Salvia N; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Kopach O; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.; Neuroscience and Cell Biology Research Institute, City St George's, University of London, Cranmer Terrace, London SW17 0RE, UK., Evans JR; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Rodrigues M; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK., Lopez-Garcia P; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Lachica J; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Clarke BE; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Department of Neuromuscular Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK., Singh J; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Ghareeb A; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK., Bayne J; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK.; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Grant-Peters M; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Garcia-Ruiz S; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Chen Z; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Rodriques S; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK.; FutureHouse, 1405 Minnesota Street, San Francisco, CA 94107, USA., Athauda D; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK., Gustavsson EK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Gagliano Taliun SA; Montréal Heart Institute, Montréal, QC, Canada.; Department of Medicine and Department of Neurosciences, Université de Montréal, Montréal, QC, Canada., Toomey C; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Reynolds RH; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Young G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; MRC Laboratory of Medical Sciences, London W12 0HS, UK., Strohbuecker S; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Warner T; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Rusakov DA; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK., Patani R; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Department of Neuromuscular Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK., Bryant C; Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK., Klenerman DA; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK., Gandhi S; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Ryten M; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK.; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, UK.; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. |
| Source: | Science advances [Sci Adv] 2025 Apr 11; Vol. 11 (15), pp. eadp8504. Date of Electronic Publication: 2025 Apr 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40215316 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Astrocytic RNA editing regulates the host immune response to alpha-synuclein. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22D'Sa+K%22">D'Sa K</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Choi+ML%22">Choi ML</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Brain & Cognitive Sciences, KAIST, 921 Dehak-ro, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Wagen+AZ%22">Wagen AZ</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.<br /><searchLink fieldCode="AU" term="%22Setó-Salvia+N%22">Setó-Salvia N</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Kopach+O%22">Kopach O</searchLink>; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.; Neuroscience and Cell Biology Research Institute, City St George's, University of London, Cranmer Terrace, London SW17 0RE, UK.<br /><searchLink fieldCode="AU" term="%22Evans+JR%22">Evans JR</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Rodrigues+M%22">Rodrigues M</searchLink>; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK.<br /><searchLink fieldCode="AU" term="%22Lopez-Garcia+P%22">Lopez-Garcia P</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Lachica+J%22">Lachica J</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Clarke+BE%22">Clarke BE</searchLink>; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Department of Neuromuscular Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Singh+J%22">Singh J</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Ghareeb+A%22">Ghareeb A</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Bayne+J%22">Bayne J</searchLink>; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK.; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK.<br /><searchLink fieldCode="AU" term="%22Grant-Peters+M%22">Grant-Peters M</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.<br /><searchLink fieldCode="AU" term="%22Garcia-Ruiz+S%22">Garcia-Ruiz S</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Rodriques+S%22">Rodriques S</searchLink>; Applied Biotechnology Lab, The Francis Crick Institute, London NW1 1AT, UK.; FutureHouse, 1405 Minnesota Street, San Francisco, CA 94107, USA.<br /><searchLink fieldCode="AU" term="%22Athauda+D%22">Athauda D</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Gustavsson+EK%22">Gustavsson EK</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Gagliano+Taliun+SA%22">Gagliano Taliun SA</searchLink>; Montréal Heart Institute, Montréal, QC, Canada.; Department of Medicine and Department of Neurosciences, Université de Montréal, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Toomey+C%22">Toomey C</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Reynolds+RH%22">Reynolds RH</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.<br /><searchLink fieldCode="AU" term="%22Young+G%22">Young G</searchLink>; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; MRC Laboratory of Medical Sciences, London W12 0HS, UK.<br /><searchLink fieldCode="AU" term="%22Strohbuecker+S%22">Strohbuecker S</searchLink>; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Warner+T%22">Warner T</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Rusakov+DA%22">Rusakov DA</searchLink>; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Patani+R%22">Patani R</searchLink>; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Department of Neuromuscular Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Bryant+C%22">Bryant C</searchLink>; Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+DA%22">Klenerman DA</searchLink>; Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK.<br /><searchLink fieldCode="AU" term="%22Gandhi+S%22">Gandhi S</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Ryten+M%22">Ryten M</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.; UK Dementia Research Institute at The University of Cambridge, Cambridge CB2 0AH, UK.; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, UK.; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2025 Apr 11; Vol. 11 (15), pp. eadp8504. <i>Date of Electronic Publication: </i>2025 Apr 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101653440 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2375-2548 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223752548%22">23752548 </searchLink><i>NLM ISO Abbreviation: </i>Sci Adv <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/sciadv.adp8504 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eadp8504 Titles: – TitleFull: Astrocytic RNA editing regulates the host immune response to alpha-synuclein. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: D'Sa K – PersonEntity: Name: NameFull: Choi ML – PersonEntity: Name: NameFull: Wagen AZ – PersonEntity: Name: NameFull: Setó-Salvia N – PersonEntity: Name: NameFull: Kopach O – PersonEntity: Name: NameFull: Evans JR – PersonEntity: Name: NameFull: Rodrigues M – PersonEntity: Name: NameFull: Lopez-Garcia P – PersonEntity: Name: NameFull: Lachica J – PersonEntity: Name: NameFull: Clarke BE – PersonEntity: Name: NameFull: Singh J – PersonEntity: Name: NameFull: Ghareeb A – PersonEntity: Name: NameFull: Bayne J – PersonEntity: Name: NameFull: Grant-Peters M – PersonEntity: Name: NameFull: Garcia-Ruiz S – PersonEntity: Name: NameFull: Chen Z – PersonEntity: Name: NameFull: Rodriques S – PersonEntity: Name: NameFull: Athauda D – PersonEntity: Name: NameFull: Gustavsson EK – PersonEntity: Name: NameFull: Gagliano Taliun SA – PersonEntity: Name: NameFull: Toomey C – PersonEntity: Name: NameFull: Reynolds RH – PersonEntity: Name: NameFull: Young G – PersonEntity: Name: NameFull: Strohbuecker S – PersonEntity: Name: NameFull: Warner T – PersonEntity: Name: NameFull: Rusakov DA – PersonEntity: Name: NameFull: Patani R – PersonEntity: Name: NameFull: Bryant C – PersonEntity: Name: NameFull: Klenerman DA – PersonEntity: Name: NameFull: Gandhi S – PersonEntity: Name: NameFull: Ryten M IsPartOfRelationships: – BibEntity: Dates: – D: 11 M: 04 Text: 2025 Apr 11 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2375-2548 Numbering: – Type: volume Value: 11 – Type: issue Value: 15 Titles: – TitleFull: Science advances Type: main |
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