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A phase I/II trial evaluating the safety of increased-dose S- 1 with oxaliplatin and nivolumab in HER2-negative advanced gastric cancer.

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Title: A phase I/II trial evaluating the safety of increased-dose S- 1 with oxaliplatin and nivolumab in HER2-negative advanced gastric cancer.
Authors: Baba K; Department of Oncology and General Medicine, IMSUT Hospital, the Institute of Medical Science Hospital, the University of Tokyo, Tokyo, Japan., Suzuki N; Department of Gastroenterology Graduate School of Medicine, University of Tokyo, Tokyo, Japan., Imamura CK; Advanced Cancer Translational Research Institute, Showa University, Tokyo, Japan., Booka E; Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan., Takeuchi M; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Takahari D; Department of Gastroenterological Chemotherapy, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan., Kawakami T; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan., Kawakubo H; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Kitagawa C; Medical Oncology and Respiratory Medicine, NHO Nagoya Medical Center, Aichi, Japan., Kono Y; Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan., Ogura K; Department of Gastroenterology, Tokyo Metropolitan Police Hospital, Tokyo, Japan., Kito Y; Department of Medical Oncology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan., Saito K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan., Yamamoto S; Department of Gastroenterology, Japanese Red Cross Medical Center, Tokyo, Japan., Takeuchi H; Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan., Kudo T; Department of Medical Oncology, Osaka International Cancer Institute, Osaka, Japan., Tsunoda T; Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan., Mizukami T; Department of Medical Oncology, NTT Medical Center Tokyo, Tokyo, Japan., Yamaguchi T; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan., Shoji H; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan., Saito K; Department of Medical Oncology, Mie University Hospital, Mie, Japan., Tanoue K; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Baba E; Department of Comprehensive Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Nagashima K; Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan., Boku N; Department of Oncology and General Medicine, IMSUT Hospital, the Institute of Medical Science Hospital, the University of Tokyo, Tokyo, Japan. nboku@ims.u-tokyo.ac.jp.
Source: BMC cancer [BMC Cancer] 2025 Apr 12; Vol. 25 (1), pp. 675. Date of Electronic Publication: 2025 Apr 12.
Publication Type: Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A phase I/II trial evaluating the safety of increased-dose S- 1 with oxaliplatin and nivolumab in HER2-negative advanced gastric cancer.
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  Data: <searchLink fieldCode="AU" term="%22Baba+K%22">Baba K</searchLink>; Department of Oncology and General Medicine, IMSUT Hospital, the Institute of Medical Science Hospital, the University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+N%22">Suzuki N</searchLink>; Department of Gastroenterology Graduate School of Medicine, University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Imamura+CK%22">Imamura CK</searchLink>; Advanced Cancer Translational Research Institute, Showa University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Booka+E%22">Booka E</searchLink>; Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+M%22">Takeuchi M</searchLink>; Department of Surgery, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takahari+D%22">Takahari D</searchLink>; Department of Gastroenterological Chemotherapy, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawakami+T%22">Kawakami T</searchLink>; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kawakubo+H%22">Kawakubo H</searchLink>; Department of Surgery, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kitagawa+C%22">Kitagawa C</searchLink>; Medical Oncology and Respiratory Medicine, NHO Nagoya Medical Center, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Kono+Y%22">Kono Y</searchLink>; Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Ogura+K%22">Ogura K</searchLink>; Department of Gastroenterology, Tokyo Metropolitan Police Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kito+Y%22">Kito Y</searchLink>; Department of Medical Oncology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+K%22">Saito K</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+S%22">Yamamoto S</searchLink>; Department of Gastroenterology, Japanese Red Cross Medical Center, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+H%22">Takeuchi H</searchLink>; Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Kudo+T%22">Kudo T</searchLink>; Department of Medical Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tsunoda+T%22">Tsunoda T</searchLink>; Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mizukami+T%22">Mizukami T</searchLink>; Department of Medical Oncology, NTT Medical Center Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+T%22">Yamaguchi T</searchLink>; Cancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shoji+H%22">Shoji H</searchLink>; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+K%22">Saito K</searchLink>; Department of Medical Oncology, Mie University Hospital, Mie, Japan.<br /><searchLink fieldCode="AU" term="%22Tanoue+K%22">Tanoue K</searchLink>; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Baba+E%22">Baba E</searchLink>; Department of Comprehensive Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Nagashima+K%22">Nagashima K</searchLink>; Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Boku+N%22">Boku N</searchLink>; Department of Oncology and General Medicine, IMSUT Hospital, the Institute of Medical Science Hospital, the University of Tokyo, Tokyo, Japan. nboku@ims.u-tokyo.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2025 Apr 12; Vol. 25 (1), pp. 675. <i>Date of Electronic Publication: </i>2025 Apr 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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