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Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation.

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Title: Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation.
Authors: Palli E; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece., Lavigne M; Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology - Biology Department, University of Crete, School of Medicine, Heraklion, Greece., Verginis P; Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology - Biology Department, University of Crete, School of Medicine, Heraklion, Greece., Alissafi T; Laboratory of Biology, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece., Anastasopoulou A; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece., Lyrarakis G; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece., Kirkwood JM; Division of Hematology/Oncology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, United States., Gogas H; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece., Ziogas DC; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.
Source: Frontiers in immunology [Front Immunol] 2025 Mar 28; Vol. 16, pp. 1529707. Date of Electronic Publication: 2025 Mar 28 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptomic signatures in peripheral CD4<superscript>+</superscript>T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation.
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  Data: <searchLink fieldCode="AU" term="%22Palli+E%22">Palli E</searchLink>; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Lavigne+M%22">Lavigne M</searchLink>; Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology - Biology Department, University of Crete, School of Medicine, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Verginis+P%22">Verginis P</searchLink>; Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology - Biology Department, University of Crete, School of Medicine, Heraklion, Greece.<br /><searchLink fieldCode="AU" term="%22Alissafi+T%22">Alissafi T</searchLink>; Laboratory of Biology, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Anastasopoulou+A%22">Anastasopoulou A</searchLink>; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Lyrarakis+G%22">Lyrarakis G</searchLink>; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Kirkwood+JM%22">Kirkwood JM</searchLink>; Division of Hematology/Oncology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Gogas+H%22">Gogas H</searchLink>; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Ziogas+DC%22">Ziogas DC</searchLink>; First Department of Internal Medicine, Laikon General Hospital, National and Kapodistrian University of Athens - School of Medicine, Athens, Greece.
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