Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes.
Saved in:
| Title: | Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes. |
|---|---|
| Authors: | Sievers P; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Arora S; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Hielscher T; Department of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Savran D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Schrimpf D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Banan R; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Vonhören D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Pusch S; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Sill M; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany., Appay R; Institute of Neurophysiopathol, CNRS, INP, Aix-Marseille University, Marseille, France.; Department of Pathology and Neuropathology, APHM, CHU Timone, Marseille, France., Wirsching HG; Department of Neurology, Clinical Neuroscience Center and Brain Tumor Center, University Hospital Zurich, Zurich, Switzerland., Hortobagyi T; Department of Neuropathology, University Hospital Zurich, Zurich, Switzerland., Dohmen H; Institute of Neuropathology, Justus-Liebig University Giessen, Giessen, Germany., Acker T; Department of Pathology, Klinikum Stuttgart, Stuttgart, Germany.; Institute of Neuropathology, Justus-Liebig University Giessen, Giessen, Germany., Kohlhof-Meinecke P, Schweizer L; Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Neurology (Edinger Institute), University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany., Wefers AK; Department of Neuropathology, Regensburg University Hospital, Regensburg, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Harter PN; Bavarian Cancer Research Center (BZKF), 91054, Erlangen, Germany.; Center for Neuropathology and Prion Research, Faculty of Medicine LMU Munich, Ludwig-Maximilians-University (LMU), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, A Partnership Between the DKFZ Heidelberg and the University Hospital of the LMU, Munich, Germany., Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School (MHH), Hannover, Germany., Beschorner R; Center for Neuro-Oncology, Comprehensive Cancer Center Tübingen-Stuttgart, University Hospital Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany.; Department of Neuropathology, University of Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany., Schittenhelm J; Center for Neuro-Oncology, Comprehensive Cancer Center Tübingen-Stuttgart, University Hospital Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany.; Department of Neuropathology, University of Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany., Behling F; Hertie Institute for Clinical Brain Research, Eberhard Karls University Tübingen, Tübingen, Germany.; Department of Neurosurgery, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.; Center for Neuro-Oncology, Comprehensive Cancer Center Tübingen-Stuttgart, University Hospital Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany.; Department of Neurology and Interdisciplinary Neuro-Oncology, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen, >Germany., Tabatabai G; Hertie Institute for Clinical Brain Research, Eberhard Karls University Tübingen, Tübingen, Germany.; Center for Neuro-Oncology, Comprehensive Cancer Center Tübingen-Stuttgart, University Hospital Tübingen, Eberhard-Karls-University Tübingen, Tübingen, Germany.; Department of Neurology and Interdisciplinary Neuro-Oncology, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany., Mawrin C; Department of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany., Snuderl M; Department of Pathology, NYU Langone Medical Center, New York, NY, USA., Maas SLN; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Wesseling P; Department of Pathology, Amsterdam University Medical Centers, Location VUmc and Brain Tumor Center Amsterdam, Amsterdam, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Brandner S; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, UK., Korshunov A; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Ratliff M; Clinical Cooperation Unit Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurosurgery Clinic, University Hospital Mannheim, Mannheim, Germany., Krieg SM; Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany., Wick W; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Jones DTW; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Germany.; Division of Pediatric Glioma Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany., Pfister SM; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Germany.; Division of Pediatric Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany., Holland EC; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., von Deimling A; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Szulzewsky F; Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA., Sahm F; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Germany.; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. |
| Source: | Neuro-oncology [Neuro Oncol] 2025 Oct 14; Vol. 27 (9), pp. 2326-2340. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
