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CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity.

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Title: CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity.
Authors: Fosch A; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Pizarro DS; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Zagmutt S; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Reguera AC; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Batallé G; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Rodríguez-García M; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., García-Chica J; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain., Freire-Agulleiro O; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain., Miralpeix C; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France., Zizzari P; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France., Serra D; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, 08028 Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Herrero L; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, 08028 Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., López M; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain., Cota D; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France., Rodríguez-Rodríguez R; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address: rrodriguez@uic.es., Casals N; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address: ncasals@uic.es.
Source: Molecular metabolism [Mol Metab] 2025 Jun; Vol. 96, pp. 102155. Date of Electronic Publication: 2025 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE
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  Data: CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity.
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  Data: <searchLink fieldCode="AU" term="%22Fosch+A%22">Fosch A</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Pizarro+DS%22">Pizarro DS</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Zagmutt+S%22">Zagmutt S</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Reguera+AC%22">Reguera AC</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Batallé+G%22">Batallé G</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-García+M%22">Rodríguez-García M</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22García-Chica+J%22">García-Chica J</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain.<br /><searchLink fieldCode="AU" term="%22Freire-Agulleiro+O%22">Freire-Agulleiro O</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain.<br /><searchLink fieldCode="AU" term="%22Miralpeix+C%22">Miralpeix C</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Zizzari+P%22">Zizzari P</searchLink>; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Serra+D%22">Serra D</searchLink>; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, 08028 Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Herrero+L%22">Herrero L</searchLink>; Department of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Barcelona, 08028 Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López+M%22">López M</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cota+D%22">Cota D</searchLink>; INSERM, Neurocentre Magendie, U1215, University of Bordeaux, 3300 Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Rodríguez+R%22">Rodríguez-Rodríguez R</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address: rrodriguez@uic.es.<br /><searchLink fieldCode="AU" term="%22Casals+N%22">Casals N</searchLink>; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallès, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address: ncasals@uic.es.
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