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Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression.

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Title: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression.
Authors: Brugia F; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Ivanov K; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., Aroviita A; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., Giniatullina R; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Lehtonen M; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland., Malm T; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Savinainen J; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., Giniatullin R; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Della Pietra A; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. adellapietra@uiowa.edu.
Source: The journal of headache and pain [J Headache Pain] 2025 Apr 23; Vol. 26 (1), pp. 85. Date of Electronic Publication: 2025 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression.
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  Data: <searchLink fieldCode="AU" term="%22Brugia+F%22">Brugia F</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Ivanov+K%22">Ivanov K</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Aroviita+A%22">Aroviita A</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Giniatullina+R%22">Giniatullina R</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Lehtonen+M%22">Lehtonen M</searchLink>; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Malm+T%22">Malm T</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Savinainen+J%22">Savinainen J</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Giniatullin+R%22">Giniatullin R</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Della+Pietra+A%22">Della Pietra A</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. adellapietra@uiowa.edu.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2025 Apr 23; Vol. 26 (1), pp. 85. <i>Date of Electronic Publication: </i>2025 Apr 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s10194-025-02030-2
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        Text: English
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        StartPage: 85
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      – TitleFull: Inhibition of endocannabinoid hydrolases MAGL, FAAH and ABHD6 by AKU-005 reduces ex vivo cortical spreading depression.
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              Text: 2025 Apr 23
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