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Personalized treatment decision algorithms for the clinical application of serum neurofilament light chain in multiple sclerosis: A modified Delphi Study.

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Title: Personalized treatment decision algorithms for the clinical application of serum neurofilament light chain in multiple sclerosis: A modified Delphi Study.
Authors: Yaldizli Ö; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.; Translational Imaging in Neurology Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel, University of Basel, Basel, Switzerland., Benkert P; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland., Achtnichts L; Neurozentrum Oberaargau, Langenthal, Switzerland., Bar-Or A; Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bohner-Lang V; Patient Consultant, Basel, Switzerland., Bridel C; Translational Biomarker Research Group, Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Comabella M; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain., Findling O; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland., Disanto G; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland., Finkener S; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland., Gobbi C; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland., Granziera C; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.; Translational Imaging in Neurology Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel, University of Basel, Basel, Switzerland., Herwerth M; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Hoepner R; Department of Neurology, Bern University Hospital, University of Bern, Bern, Switzerland., Horakova D; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic., Kamber N; Division of Neurology, Department of Internal Medicine, Bürgerspital Solothurn, Solothurn, Switzerland., Khalil M; Department of Neurology, Medical University of Graz, Graz, Austria., Kunz P; Patient Consultant, Basel, Switzerland., Lalive P; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland., Linker R; Department of Neurology, University of Regensburg, Regensburg, Germany., Lorscheider J; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland., Müller S; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland., Oechtering J; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland., Pettypool V; Patient Consultant, Basel, Switzerland., Piehl F; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Neuroimmunology Unit, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden., Pot C; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland., Roth P; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Théaudin M; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland., Tintore M; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain., Tur C; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain., Uffer D; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland., Uginet M; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland., Vehoff J; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland., Wiendl H; Department of Neurology, Institute of Translational Neurology, University Hospital Münster, Münster, Germany., Ziemssen T; Center of Clinical Neuroscience, Neurological Clinic, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany., Zecca C; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland., Salmen A; Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Bochum, Germany., Leppert D; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Derfuss T; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland., Kappos L; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Hemkens LG; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Janiaud P; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland., Kuhle J; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland.; Multiple Sclerosis Centre, University Hospital Basel, Basel, Switzerland.
Source: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2025 Jul; Vol. 31 (8), pp. 932-943. Date of Electronic Publication: 2025 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Personalized treatment decision algorithms for the clinical application of serum neurofilament light chain in multiple sclerosis: A modified Delphi Study.
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  Data: <searchLink fieldCode="AU" term="%22Yaldizli+Ö%22">Yaldizli Ö</searchLink>; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.; Translational Imaging in Neurology Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Benkert+P%22">Benkert P</searchLink>; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Achtnichts+L%22">Achtnichts L</searchLink>; Neurozentrum Oberaargau, Langenthal, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bar-Or+A%22">Bar-Or A</searchLink>; Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bohner-Lang+V%22">Bohner-Lang V</searchLink>; Patient Consultant, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bridel+C%22">Bridel C</searchLink>; Translational Biomarker Research Group, Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Comabella+M%22">Comabella M</searchLink>; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Findling+O%22">Findling O</searchLink>; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland.<br /><searchLink fieldCode="AU" term="%22Disanto+G%22">Disanto G</searchLink>; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Finkener+S%22">Finkener S</searchLink>; Department of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gobbi+C%22">Gobbi C</searchLink>; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Granziera+C%22">Granziera C</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.; Translational Imaging in Neurology Basel, Department of Medicine and Biomedical Engineering, University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Herwerth+M%22">Herwerth M</searchLink>; Department of Neurology, University Hospital Zurich, Zurich, Switzerland.; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoepner+R%22">Hoepner R</searchLink>; Department of Neurology, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Horakova+D%22">Horakova D</searchLink>; Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kamber+N%22">Kamber N</searchLink>; Division of Neurology, Department of Internal Medicine, Bürgerspital Solothurn, Solothurn, Switzerland.<br /><searchLink fieldCode="AU" term="%22Khalil+M%22">Khalil M</searchLink>; Department of Neurology, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Kunz+P%22">Kunz P</searchLink>; Patient Consultant, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lalive+P%22">Lalive P</searchLink>; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Linker+R%22">Linker R</searchLink>; Department of Neurology, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lorscheider+J%22">Lorscheider J</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Müller+S%22">Müller S</searchLink>; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Oechtering+J%22">Oechtering J</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pettypool+V%22">Pettypool V</searchLink>; Patient Consultant, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Piehl+F%22">Piehl F</searchLink>; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.; Neuroimmunology Unit, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Pot+C%22">Pot C</searchLink>; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Roth+P%22">Roth P</searchLink>; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Théaudin+M%22">Théaudin M</searchLink>; Service of Neurology, Department of Clinical Neurosciences, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tintore+M%22">Tintore M</searchLink>; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tur+C%22">Tur C</searchLink>; Multiple Sclerosis Centre of Catalonia (Cemcat), Vall d'Hebron Barcelona Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Uffer+D%22">Uffer D</searchLink>; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Uginet+M%22">Uginet M</searchLink>; Division of Neurology, Department of Clinical Neurosciences, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vehoff+J%22">Vehoff J</searchLink>; Department of Neurology, University Teaching and Research Hospital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wiendl+H%22">Wiendl H</searchLink>; Department of Neurology, Institute of Translational Neurology, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Ziemssen+T%22">Ziemssen T</searchLink>; Center of Clinical Neuroscience, Neurological Clinic, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Zecca+C%22">Zecca C</searchLink>; Multiple Sclerosis Center, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano (EOC), Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Salmen+A%22">Salmen A</searchLink>; Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Leppert+D%22">Leppert D</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Derfuss+T%22">Derfuss T</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Neurologic Clinic and Policlinic, MS Centre, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kappos+L%22">Kappos L</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hemkens+LG%22">Hemkens LG</searchLink>; Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Janiaud+P%22">Janiaud P</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kuhle+J%22">Kuhle J</searchLink>; Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.; Department of Neurology, University Hospital Basel, University of Basel, Basel, Switzerland.; Multiple Sclerosis Centre, University Hospital Basel, Basel, Switzerland.
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