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Mepolizumab for COPD with Eosinophilic Phenotype following Hospitalization.

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Title: Mepolizumab for COPD with Eosinophilic Phenotype following Hospitalization.
Authors: Flynn CA; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., McAuley HJC; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Elneima O; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Aung HWW; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Ibrahim W; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Ward TJC; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Bourne M; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Thornton TD; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Mistry V; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Gilbert HR; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK., Waheed G; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK., Wright AKA; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Evans RA; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Steiner MC; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Brookes CL; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK., Brightling CE; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK., Greening NJ; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.
Source: NEJM evidence [NEJM Evid] 2025 Jun; Vol. 4 (6), pp. EVIDoa2500012. Date of Electronic Publication: 2025 Apr 30.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: NEJM Group, a division of the Massachusetts Medical Society Country of Publication: United States NLM ID: 9918317485806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2766-5526 (Electronic) Linking ISSN: 27665526 NLM ISO Abbreviation: NEJM Evid Subsets: MEDLINE
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  Data: Mepolizumab for COPD with Eosinophilic Phenotype following Hospitalization.
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  Data: <searchLink fieldCode="AU" term="%22Flynn+CA%22">Flynn CA</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22McAuley+HJC%22">McAuley HJC</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Elneima+O%22">Elneima O</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Aung+HWW%22">Aung HWW</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Ibrahim+W%22">Ibrahim W</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Ward+TJC%22">Ward TJC</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Bourne+M%22">Bourne M</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Thornton+TD%22">Thornton TD</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Mistry+V%22">Mistry V</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Gilbert+HR%22">Gilbert HR</searchLink>; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Waheed+G%22">Waheed G</searchLink>; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Wright+AKA%22">Wright AKA</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Evans+RA%22">Evans RA</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Steiner+MC%22">Steiner MC</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Brookes+CL%22">Brookes CL</searchLink>; Leicester Clinical Trials Unit, College of Life Sciences, University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Brightling+CE%22">Brightling CE</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Greening+NJ%22">Greening NJ</searchLink>; Institute for Lung Health, National Institute for Health and Care Research Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.
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        Value: 10.1056/EVIDoa2500012
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        Text: English
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              Text: 2025 Jun
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