Anthocyanin supplementation in adults at risk for dementia: a randomized controlled trial on its cardiometabolic and anti-inflammatory biomarker effects.

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Title: Anthocyanin supplementation in adults at risk for dementia: a randomized controlled trial on its cardiometabolic and anti-inflammatory biomarker effects.
Authors: Borda MG; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway. mmborda@gmail.com.; Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain. mmborda@gmail.com.; Centro de Investigación en Ciencias de La Salud (CICSA), FCS, Universidad Anáhuac México, Huixquilucan Edo. de México, México. mmborda@gmail.com., Ramírez-Vélez R; Navarrabiomed, IdiSNA, Hospital Universitario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Pamplona, Spain., Botero-Rodriguez F; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; SynaptIA - Inteligencia artificial para la investigación en salud mental, Bogotá, Colombia.; Centro de Memoria y Cognición Intellectus, Hospital Universitario San Ignacio, Bogotá, Colombia., Patricio-Baldera J; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Instituto de Investigación en Salud, Facultad de Ciencias de La Salud de La Universidad Autónoma de Santo Domingo, Santo Domingo, Dominican Republic., de Lucia C; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Pola I; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden., Barreto GE; Department of Biological Sciences, University of Limerick, Limerick, Ireland., Khalifa K; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway., Bergland AK; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway., Kivipelto M; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Cederholm T; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 62167, Uppsala, Sweden.; Theme Inflammation & Ageing, Karolinska University Hospital, Stockholm, Sweden., Zetterberg H; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK, Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin, University of Wisconsin-Madison, Madison, WI, USA., Ashton NJ; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.; Banner Alzheimer's Institute, University of Arizona, Phoenix, AZ, USA., Ballard C; Medical School, University of Exeter, University of Exeter, Exeter, UK., Siow R; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.; School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Sciences & Medicine, British Heart Foundation Centre of Research Excellence, King's College London, London, UK., Aarsland D; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
Corporate Authors: NJ FINGER
Source: GeroScience [Geroscience] 2026 Feb; Vol. 48 (1), pp. 563-576. Date of Electronic Publication: 2025 May 02.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anthocyanin supplementation in adults at risk for dementia: a randomized controlled trial on its cardiometabolic and anti-inflammatory biomarker effects.
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  Data: <searchLink fieldCode="AU" term="%22Borda+MG%22">Borda MG</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway. mmborda@gmail.com.; Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain. mmborda@gmail.com.; Centro de Investigación en Ciencias de La Salud (CICSA), FCS, Universidad Anáhuac México, Huixquilucan Edo. de México, México. mmborda@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ramírez-Vélez+R%22">Ramírez-Vélez R</searchLink>; Navarrabiomed, IdiSNA, Hospital Universitario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Botero-Rodriguez+F%22">Botero-Rodriguez F</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; SynaptIA - Inteligencia artificial para la investigación en salud mental, Bogotá, Colombia.; Centro de Memoria y Cognición Intellectus, Hospital Universitario San Ignacio, Bogotá, Colombia.<br /><searchLink fieldCode="AU" term="%22Patricio-Baldera+J%22">Patricio-Baldera J</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Instituto de Investigación en Salud, Facultad de Ciencias de La Salud de La Universidad Autónoma de Santo Domingo, Santo Domingo, Dominican Republic.<br /><searchLink fieldCode="AU" term="%22de+Lucia+C%22">de Lucia C</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pola+I%22">Pola I</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Barreto+GE%22">Barreto GE</searchLink>; Department of Biological Sciences, University of Limerick, Limerick, Ireland.<br /><searchLink fieldCode="AU" term="%22Khalifa+K%22">Khalifa K</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.<br /><searchLink fieldCode="AU" term="%22Bergland+AK%22">Bergland AK</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Kivipelto+M%22">Kivipelto M</searchLink>; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Cederholm+T%22">Cederholm T</searchLink>; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 62167, Uppsala, Sweden.; Theme Inflammation & Ageing, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.; UK, Dementia Research Institute at UCL, London, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.; Banner Alzheimer's Institute, University of Arizona, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Ballard+C%22">Ballard C</searchLink>; Medical School, University of Exeter, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Siow+R%22">Siow R</searchLink>; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.; School of Cardiovascular and Metabolic Medicine & Sciences, Faculty of Life Sciences & Medicine, British Heart Foundation Centre of Research Excellence, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Aarsland+D%22">Aarsland D</searchLink>; Centre for Age-Related Medicine (SESAM), Stavanger University Hospital, Helse Stavanger HF, Postboks 8100, 4068, Stavanger, Norway.; Centre for Healthy Brain Ageing, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2026 Feb; Vol. 48 (1), pp. 563-576. <i>Date of Electronic Publication: </i>2025 May 02.
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