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DSG2 attenuates gemcitabine efficacy through PTX3 in lung adenocarcinoma.

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Title: DSG2 attenuates gemcitabine efficacy through PTX3 in lung adenocarcinoma.
Authors: Wang CC; Divisions of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan., Lin JY; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan., Wang CY; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan., Shen WJ; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan., Liao PC; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan., Ho YF; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan., Lin CW; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan., Wang SA; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan., Ko CC; Department of Medical Imaging, Chi-Mei Medical Center, Tainan, Taiwan; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan., Dey S; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan., Ta HDK; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan., Xuan DTM; Faculty of Pharmacy, Van Lang University, 69/68 Dang Thuy Tram Street, Ward 13, Binh Thanh District, Ho Chi Minh City 70000, Viet Nam., Kumar S; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India., William BT; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Department of Biomedicine, School of Life Sciences, Indonesia International Institute for Life Sciences, Jl Pulomas Barat Kav 88, Jakarta Timur 13210, Indonesia., Wang JM; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Wang WJ; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan; Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung 40402, Taiwan. Electronic address: cvcsky@cmu.edu.tw.
Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Aug; Vol. 1871 (6), pp. 167881. Date of Electronic Publication: 2025 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE
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  Data: DSG2 attenuates gemcitabine efficacy through PTX3 in lung adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Wang+CC%22">Wang CC</searchLink>; Divisions of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+JY%22">Lin JY</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CY%22">Wang CY</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+WJ%22">Shen WJ</searchLink>; Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 40402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+PC%22">Liao PC</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+YF%22">Ho YF</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CW%22">Lin CW</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+SA%22">Wang SA</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ko+CC%22">Ko CC</searchLink>; Department of Medical Imaging, Chi-Mei Medical Center, Tainan, Taiwan; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Dey+S%22">Dey S</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ta+HDK%22">Ta HDK</searchLink>; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Xuan+DTM%22">Xuan DTM</searchLink>; Faculty of Pharmacy, Van Lang University, 69/68 Dang Thuy Tram Street, Ward 13, Binh Thanh District, Ho Chi Minh City 70000, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India.<br /><searchLink fieldCode="AU" term="%22William+BT%22">William BT</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Department of Biomedicine, School of Life Sciences, Indonesia International Institute for Life Sciences, Jl Pulomas Barat Kav 88, Jakarta Timur 13210, Indonesia.<br /><searchLink fieldCode="AU" term="%22Wang+JM%22">Wang JM</searchLink>; Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+WJ%22">Wang WJ</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung 40676, Taiwan; Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung 40402, Taiwan. Electronic address: cvcsky@cmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101731730%22">Biochimica et biophysica acta. Molecular basis of disease</searchLink> [Biochim Biophys Acta Mol Basis Dis] 2025 Aug; Vol. 1871 (6), pp. 167881. <i>Date of Electronic Publication: </i>2025 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101731730 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-260X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209254439%22">09254439 </searchLink><i>NLM ISO Abbreviation: </i>Biochim Biophys Acta Mol Basis Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbadis.2025.167881
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      – Code: eng
        Text: English
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      – TitleFull: DSG2 attenuates gemcitabine efficacy through PTX3 in lung adenocarcinoma.
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              Text: 2025 Aug
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              Y: 2025
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