Predictive value of the polygenic risk score for developing epilepsy: a systematic review and meta-analysis.

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Title: Predictive value of the polygenic risk score for developing epilepsy: a systematic review and meta-analysis.
Authors: Kubota T; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania. Electronic address: takafumi.kubota.c7@tohoku.ac.jp., Ngadimon IW; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Neuropharmacology Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia., Ohseto H; Department of Molecular Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan., Viswanathan S; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Paediatrics, Penang General Hospital, Georgetown, Pulau Pinang, Malaysia., Ravat P; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Neurology, Flinders Medical Centre, Adelaide, South Australia, Australia., Acharya MK; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Dr. B C Roy Multispecialty Medical Research Centre, Indian Institute of Technology, Kharagpur, India., Kuroda N; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Pediatrics, Wayne State University, Detroit, MI, USA., Konomatsu K; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan., Obara T; Department of Molecular Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan., Jin K; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. Electronic address: kazutaka.jin.e8@tohoku.ac.jp., Aoki M; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan., Nakasato N; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Source: Epilepsy & behavior : E&B [Epilepsy Behav] 2025 Aug; Vol. 169, pp. 110438. Date of Electronic Publication: 2025 May 03.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 100892858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-5069 (Electronic) Linking ISSN: 15255050 NLM ISO Abbreviation: Epilepsy Behav Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kubota+T%22">Kubota T</searchLink>; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania. Electronic address: takafumi.kubota.c7@tohoku.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ngadimon+IW%22">Ngadimon IW</searchLink>; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Neuropharmacology Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ohseto+H%22">Ohseto H</searchLink>; Department of Molecular Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Viswanathan+S%22">Viswanathan S</searchLink>; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Paediatrics, Penang General Hospital, Georgetown, Pulau Pinang, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ravat+P%22">Ravat P</searchLink>; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Neurology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Acharya+MK%22">Acharya MK</searchLink>; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Dr. B C Roy Multispecialty Medical Research Centre, Indian Institute of Technology, Kharagpur, India.<br /><searchLink fieldCode="AU" term="%22Kuroda+N%22">Kuroda N</searchLink>; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; YES-AO, a regional chapter of the Young Epilepsy Section of the International League Against Epilepsy (ILAE-YES) in Asia-Oceania; Department of Pediatrics, Wayne State University, Detroit, MI, USA.<br /><searchLink fieldCode="AU" term="%22Konomatsu+K%22">Konomatsu K</searchLink>; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Obara+T%22">Obara T</searchLink>; Department of Molecular Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Jin+K%22">Jin K</searchLink>; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. Electronic address: kazutaka.jin.e8@tohoku.ac.jp.<br /><searchLink fieldCode="AU" term="%22Aoki+M%22">Aoki M</searchLink>; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Nakasato+N%22">Nakasato N</searchLink>; Department of Epileptology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
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  Data: <searchLink fieldCode="JN" term="%22100892858%22">Epilepsy & behavior : E&B</searchLink> [Epilepsy Behav] 2025 Aug; Vol. 169, pp. 110438. <i>Date of Electronic Publication: </i>2025 May 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100892858 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-5069 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215255050%22">15255050 </searchLink><i>NLM ISO Abbreviation: </i>Epilepsy Behav <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.yebeh.2025.110438
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      – Code: eng
        Text: English
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      – TitleFull: Predictive value of the polygenic risk score for developing epilepsy: a systematic review and meta-analysis.
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              Text: 2025 Aug
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