A 24-week prospective, multicenter, real-world study on eptinezumab's effectiveness and safety in migraine prevention (EMBRACE II).

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Title: A 24-week prospective, multicenter, real-world study on eptinezumab's effectiveness and safety in migraine prevention (EMBRACE II).
Authors: Barbanti P; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy. piero.barbanti@sanraffaele.it.; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy. piero.barbanti@sanraffaele.it., Aurilia C; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy., Egeo G; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy., Doretti A; Laboratory of Neurosciences, Department of Neurology-Stroke Unit, Istituto Auxologico Italiano, IRCCS, Milano, Italy., d'Onofrio F; Stroke Unit and Headache Center Neurology Unit, San Giuseppe Moscati Hospital, Avellino, Italy., Scatena P; Department of Neurology and Stroke Unit, San Camillo de Lellis, General District Hospital, Rieti, Italy., Rinalduzzi S; Department of Neurology and Stroke Unit, San Camillo de Lellis, General District Hospital, Rieti, Italy., Vinciguerra L; Department of Neurology, ASST Crema Hospital, Crema, Italy., Sansone M; Headache Center, San Giuseppe Moscati Hospital, Aversa, Italy., Vecchio R; Neurology Unit Muscatello Hospital Augusta ASP, Siracusa, Italy., Drago V; Neurology Unit Muscatello Hospital Augusta ASP, Siracusa, Italy., Viticchi G; Neurological Clinic, Marche Polytechnic University, Ancona, Italy., Bartolini M; Neurological Clinic, Marche Polytechnic University, Ancona, Italy., Ranieri A; Headache Centre, Division of Neurology and Stroke-Unit, Antonio Cardarelli Hospital, Naples, Italy., Bandettini di Poggio M; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Baldisseri F; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Mascarella D; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Brusaferri F; Department of Neurology, ASST Crema Hospital, Crema, Italy., Caputi L; Department of Neurology, ASST Crema Hospital, Crema, Italy., Messina S; Laboratory of Neurosciences, Department of Neurology-Stroke Unit, Istituto Auxologico Italiano, IRCCS, Milano, Italy., Autunno M; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Valenza A; Department of Neuroscience, O.U. of Neurology, Headache Center, Stroke Unit, Belcolle Hospital, Viterbo, Italy., Orlando B; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy., Distefano M; Department of Neuroscience, O.U. of Neurology, Headache Center, Stroke Unit, Belcolle Hospital, Viterbo, Italy., Borrello L; Headache Center, Francesco Spaziani Hospital, Frosinone, Italy., Pistoia F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Camarda C; Department of Biomedicine, Neurosciences, and Advanced Diagnostics, University of Palermo, Palermo, Italy., Saporito G; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Querzola G; Stroke Unit, Neurology Division, and Headache Center, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan, Italy., Torelli P; Unit of Neurology, Department of Medicine and Surgery, Headache Center, University of Parma, Parma, Italy., Salerno A; Headache Center, San Giovanni Addolorata Hospital, Rome, Italy., Gragnani F; Headache Center, Sandro Pertini Hospital, Rome, Italy., Petolicchio B; Headache Center, Sandro Pertini Hospital, Rome, Italy., Carnevale A; Headache Center, San Filippo Neri Hospital, Rome, Italy., Messina R; Department of Neurology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Filippi M; Department of Neurology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Tavani S; Catholic University of Sacred Heart Rome, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy., Fiorentini G; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy.; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy., Bonassi S; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy.; Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Rome, Italy., Cevoli S; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Mannocci A; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy.; Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Rome, Italy.
Corporate Authors: Italian Migraine Registry (I-GRAINE) study group
Source: Journal of neurology [J Neurol] 2025 May 07; Vol. 272 (6), pp. 382. Date of Electronic Publication: 2025 May 07.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A 24-week prospective, multicenter, real-world study on eptinezumab's effectiveness and safety in migraine prevention (EMBRACE II).
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Barbanti+P%22">Barbanti P</searchLink>; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy. piero.barbanti@sanraffaele.it.; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy. piero.barbanti@sanraffaele.it.<br /><searchLink fieldCode="AU" term="%22Aurilia+C%22">Aurilia C</searchLink>; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Egeo+G%22">Egeo G</searchLink>; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Doretti+A%22">Doretti A</searchLink>; Laboratory of Neurosciences, Department of Neurology-Stroke Unit, Istituto Auxologico Italiano, IRCCS, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22d'Onofrio+F%22">d'Onofrio F</searchLink>; Stroke Unit and Headache Center Neurology Unit, San Giuseppe Moscati Hospital, Avellino, Italy.<br /><searchLink fieldCode="AU" term="%22Scatena+P%22">Scatena P</searchLink>; Department of Neurology and Stroke Unit, San Camillo de Lellis, General District Hospital, Rieti, Italy.<br /><searchLink fieldCode="AU" term="%22Rinalduzzi+S%22">Rinalduzzi S</searchLink>; Department of Neurology and Stroke Unit, San Camillo de Lellis, General District Hospital, Rieti, Italy.<br /><searchLink fieldCode="AU" term="%22Vinciguerra+L%22">Vinciguerra L</searchLink>; Department of Neurology, ASST Crema Hospital, Crema, Italy.<br /><searchLink fieldCode="AU" term="%22Sansone+M%22">Sansone M</searchLink>; Headache Center, San Giuseppe Moscati Hospital, Aversa, Italy.<br /><searchLink fieldCode="AU" term="%22Vecchio+R%22">Vecchio R</searchLink>; Neurology Unit Muscatello Hospital Augusta ASP, Siracusa, Italy.<br /><searchLink fieldCode="AU" term="%22Drago+V%22">Drago V</searchLink>; Neurology Unit Muscatello Hospital Augusta ASP, Siracusa, Italy.<br /><searchLink fieldCode="AU" term="%22Viticchi+G%22">Viticchi G</searchLink>; Neurological Clinic, Marche Polytechnic University, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Bartolini+M%22">Bartolini M</searchLink>; Neurological Clinic, Marche Polytechnic University, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Ranieri+A%22">Ranieri A</searchLink>; Headache Centre, Division of Neurology and Stroke-Unit, Antonio Cardarelli Hospital, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bandettini+di+Poggio+M%22">Bandettini di Poggio M</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Baldisseri+F%22">Baldisseri F</searchLink>; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Mascarella+D%22">Mascarella D</searchLink>; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Brusaferri+F%22">Brusaferri F</searchLink>; Department of Neurology, ASST Crema Hospital, Crema, Italy.<br /><searchLink fieldCode="AU" term="%22Caputi+L%22">Caputi L</searchLink>; Department of Neurology, ASST Crema Hospital, Crema, Italy.<br /><searchLink fieldCode="AU" term="%22Messina+S%22">Messina S</searchLink>; Laboratory of Neurosciences, Department of Neurology-Stroke Unit, Istituto Auxologico Italiano, IRCCS, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Autunno+M%22">Autunno M</searchLink>; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Valenza+A%22">Valenza A</searchLink>; Department of Neuroscience, O.U. of Neurology, Headache Center, Stroke Unit, Belcolle Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Orlando+B%22">Orlando B</searchLink>; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Distefano+M%22">Distefano M</searchLink>; Department of Neuroscience, O.U. of Neurology, Headache Center, Stroke Unit, Belcolle Hospital, Viterbo, Italy.<br /><searchLink fieldCode="AU" term="%22Borrello+L%22">Borrello L</searchLink>; Headache Center, Francesco Spaziani Hospital, Frosinone, Italy.<br /><searchLink fieldCode="AU" term="%22Pistoia+F%22">Pistoia F</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Camarda+C%22">Camarda C</searchLink>; Department of Biomedicine, Neurosciences, and Advanced Diagnostics, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Saporito+G%22">Saporito G</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Querzola+G%22">Querzola G</searchLink>; Stroke Unit, Neurology Division, and Headache Center, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Torelli+P%22">Torelli P</searchLink>; Unit of Neurology, Department of Medicine and Surgery, Headache Center, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Salerno+A%22">Salerno A</searchLink>; Headache Center, San Giovanni Addolorata Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gragnani+F%22">Gragnani F</searchLink>; Headache Center, Sandro Pertini Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Petolicchio+B%22">Petolicchio B</searchLink>; Headache Center, Sandro Pertini Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Carnevale+A%22">Carnevale A</searchLink>; Headache Center, San Filippo Neri Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Messina+R%22">Messina R</searchLink>; Department of Neurology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Filippi+M%22">Filippi M</searchLink>; Department of Neurology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tavani+S%22">Tavani S</searchLink>; Catholic University of Sacred Heart Rome, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fiorentini+G%22">Fiorentini G</searchLink>; Headache and Pain Unit, IRCCS San Raffaele Roma, Via della Pisana 235, 00163, Rome, Italy.; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bonassi+S%22">Bonassi S</searchLink>; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy.; Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cevoli+S%22">Cevoli S</searchLink>; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mannocci+A%22">Mannocci A</searchLink>; Department for the Promotion of Human Sciences and Quality of Life, University San Raffaele, Rome, Italy.; Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Rome, Italy.
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  Data: <searchLink fieldCode="CA" term="%22Italian+Migraine+Registry+%28I-GRAINE%29+study+group%22">Italian Migraine Registry (I-GRAINE) study group</searchLink>
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