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Age-associated methionine sulfoxide reductase A protects against valvular interstitial cell senescence and valvular calcification.

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Title: Age-associated methionine sulfoxide reductase A protects against valvular interstitial cell senescence and valvular calcification.
Authors: Li Q; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; National Clinical Research Center for Geriatrics, The Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China., Song C; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China., Wei Z; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, 610041, China., Zhou H; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China., Wang S; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China., Li H; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China., Yang H; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China., Luo Q; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China., Li J; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China. lijunlilily@163.com., Chen M; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China. chenmao@scu.edu.cn.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China. chenmao@scu.edu.cn.
Source: GeroScience [Geroscience] 2026 Feb; Vol. 48 (1), pp. 807-827. Date of Electronic Publication: 2025 May 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Age-associated methionine sulfoxide reductase A protects against valvular interstitial cell senescence and valvular calcification.
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  Data: <searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; National Clinical Research Center for Geriatrics, The Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Song+C%22">Song C</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Wei+Z%22">Wei Z</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Luo+Q%22">Luo Q</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China.; Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China. lijunlilily@163.com.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China. chenmao@scu.edu.cn.; Cardiac Structure and Function Research Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, China. chenmao@scu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2026 Feb; Vol. 48 (1), pp. 807-827. <i>Date of Electronic Publication: </i>2025 May 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11357-025-01675-w
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        Text: English
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              Text: 2026 Feb
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