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Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.

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Title: Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.
Authors: Shi M; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Crouse B; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Sundaram N; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Pode Shakked N; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Pediatric Nephrology Unit, Dana Dwek Children's Hospital, Tel Aviv Medical Center, Tel Aviv 6423906, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Thorner K; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., King NM; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Dutta P; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Ester L; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne and University Hospital Cologne, Cologne 50937, Germany., Zhang W; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Govindarajah V; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Kopan R; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Cebrian C; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Mayhew CN; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Helmrath MA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA., Bonventre JV; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02138, USA., McCracken KW; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: kyle.mccracken@cchmc.org.
Source: Cell stem cell [Cell Stem Cell] 2025 Jul 03; Vol. 32 (7), pp. 1055-1070.e8. Date of Electronic Publication: 2025 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.
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  Data: <searchLink fieldCode="AU" term="%22Shi+M%22">Shi M</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Crouse+B%22">Crouse B</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Sundaram+N%22">Sundaram N</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Pode+Shakked+N%22">Pode Shakked N</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Pediatric Nephrology Unit, Dana Dwek Children's Hospital, Tel Aviv Medical Center, Tel Aviv 6423906, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.<br /><searchLink fieldCode="AU" term="%22Thorner+K%22">Thorner K</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22King+NM%22">King NM</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Dutta+P%22">Dutta P</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Ester+L%22">Ester L</searchLink>; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne and University Hospital Cologne, Cologne 50937, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Govindarajah+V%22">Govindarajah V</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Kopan+R%22">Kopan R</searchLink>; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.<br /><searchLink fieldCode="AU" term="%22Cebrian+C%22">Cebrian C</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.<br /><searchLink fieldCode="AU" term="%22Mayhew+CN%22">Mayhew CN</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.<br /><searchLink fieldCode="AU" term="%22Helmrath+MA%22">Helmrath MA</searchLink>; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.<br /><searchLink fieldCode="AU" term="%22Bonventre+JV%22">Bonventre JV</searchLink>; Division of Renal Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22McCracken+KW%22">McCracken KW</searchLink>; Division of Nephrology and Hypertension, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Division of Developmental Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address: kyle.mccracken@cchmc.org.
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  Data: <searchLink fieldCode="JN" term="%22101311472%22">Cell stem cell</searchLink> [Cell Stem Cell] 2025 Jul 03; Vol. 32 (7), pp. 1055-1070.e8. <i>Date of Electronic Publication: </i>2025 May 08.
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        Value: 10.1016/j.stem.2025.04.008
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        Text: English
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              Text: 2025 Jul 03
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