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PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology.

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Title: PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology.
Authors: Messenger EJ; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Baar SA; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Bedford LM; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Tsai AP; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Lin PB; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Ferguson CA; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Xu G; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Wallace A; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA., Landreth GE; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Lamb BT; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA., Bissel SJ; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 May; Vol. 21 (5), pp. e70231.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology.
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  Data: <searchLink fieldCode="AU" term="%22Messenger+EJ%22">Messenger EJ</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Baar+SA%22">Baar SA</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Bedford+LM%22">Bedford LM</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+AP%22">Tsai AP</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Lin+PB%22">Lin PB</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+CA%22">Ferguson CA</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Xu+G%22">Xu G</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+A%22">Wallace A</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Landreth+GE%22">Landreth GE</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Lamb+BT%22">Lamb BT</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Bissel+SJ%22">Bissel SJ</searchLink>; Stark Neuroscience, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2025 May; Vol. 21 (5), pp. e70231.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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        Value: 10.1002/alz.70231
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      – Code: eng
        Text: English
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        StartPage: e70231
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      – TitleFull: PLCG2 modulates TREM2 expression and signaling in response to Alzheimer's disease pathology.
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            – D: 01
              M: 05
              Text: 2025 May
              Type: published
              Y: 2025
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